作为应用离心管柱滤器提取蛋白及亚细胞结构的先驱

英文特生物技术(北京)有限公司成功研发出五十多个全新的生命科学研究领域蛋白提取产品,其中具有多个特色产品,为蛋白提取分 离带来了新方案, 从原有的溶液法转换为柱式提取法。我公司产品 均具有快捷、易用、产量高及重复性好的特性。在短短几年中,产品 以其稳定的品质获得了世界各国越来越多的科研,药物开发及临床诊 断机构的青睐。



    订购信息:SC-003 / 4410.00元 (50 Preps)   SC-003 / 459.00元 (4 Preps)

    Minute™ 细胞质和细胞核分离试剂盒(细胞样品) SC-003

    Minute™ Cytoplasmic and Nuclear Extraction Kits for Cells

    描述:

    Minute 细胞质和细胞核分离试剂盒由细胞质提取缓冲液和细胞核提取缓冲液,离心管柱和2.0ML收集管组成。本试剂盒可快速从培养的哺乳动物细胞,原生质体(植物,细菌,酵母和真菌)中分离天然的胞质和胞核蛋白,时间<15分钟。


    应用:

    本试剂盒可以快速分离天然的胞质和胞核蛋白,可应用于SDS-PAGE, immunoblottings, ELISA, IP,蛋白质定位,凝胶迁移分析,2-D等其他应用。

    *如需分离完整的细胞核,请按需选择NI-024(无表面活性剂)SN-047(含表面活性剂)BN-020(神经元组织)AN-029(脂肪组织)


    特点:

    高得率、高效分离、简单快速。


    储存条件:

    储存于4℃

    参考文献:SC-003文献列表
    • 1. Kalabus, JL. et al. (2012). MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of common polymorphic variant rs9024. PLOS ONE. 7(11):1-9.
      2. Lombrafia AQ. et al (2014). Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without down syndrome. Pharm Res. 31:1644-1655.
      3. Hou, N., et al. (2014). Vitamin A deficiency impairs spatial learning and memory: The mechanism of abnormal CBP-dependent histone acetylation regulated by retinoic acid receptor alpha. Mol Neurobiol. DOI 10.1007/s12035-014-8741-6.
      4. You, Y., et al. (2014). Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3. Cell Death and Disease. (2014)5, e1493; doi: 10.1038/cddis. 2014.443.
      5. Tanaka M et al. (2016). Ex vivo effects of naphthoquinones allergen-sensitized mononuclear cells in mice. International Journal of Immunopathology and Pharmacology. DOI: 10.1177/0394632016632221
      6. Liu W. et al. (2016) Electroacupunctre improves motor impairment via inhibition of microglia-mediated neuroinflammation in the sensorimotor cortex after ischemic stroke. Life Sciences. doi:10.1016/j.lfs.2016.01.045
      7. Xu, Yang, et al. (2016), RIP3 induces ischemic neuronal DNA degradation and programmed necrosis in rat via AIF." Scientific Reports 6:29362.
      8. Shi, Le, et al. (2016). "Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis." Tumor Biology: 1-13.9
      9. Huang, C. W., Feng, W., Peh, M. T., Peh, K., Dymock, B. W., & Moore, P. K. (2016). A novel slow-releasing hydrogen sulfide donor, FW1256, exerts anti-inflammatory effects in mouse macrophages and in vivo. Pharmacological Research.
      10. Matsuoka, Y., Nakayama, H., Yoshida, R., Hirosue, A., Nagata, M., Tanaka, T., ... & Shinriki, S. (2016). IL-6 controls resistance to radiation by suppressing oxidative stress via the Nrf2-antioxidant pathway in oral squamous cell carcinoma. British Journal of Cancer.
      11. Chen, Y., Hu, X., Guo, C., Yu, Y., & Lu, H. (2017). Epe1 contributes to activation of AMPK by promoting phosphorylation of AMPK alpha subunit, Ssp2. Scientific Reports | 7: 3208 | DOI:10.1038/s41598-017-03442-0
      12. Meng, C., Cui, X., Qi, S., Zhang, J., Kang, J., & Zhou, H. (2016). Lung inflation with hydrogen sulfide during the warm ischemia phase ameliorates injury in rat donor lungs via metabolic inhibition after cardiac death. Surgery. DOI: http://dx.doi.org/10.1016/j.surg.2016.10.031
      13. Liu, Y., Peng, J., Sun, T., Li, N., Zhang, L., Ren, J., ... & Ding, Y. (2017).Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis. PNAS.doi: 10.1073/pnas.1700909114
      14. Hu, H., Zhu, W., Qin, J., Chen, M., Gong, L., Li, L., ... & Ye, D. (2016). Acetylation of PGK1 Promotes Liver Cancer Cell Proliferation and Tumorigenesis. Hepatology. doi: 10.1002/hep.28887
      15. Hou, Y., Wang, Y., He, Q., Li, L., Xie, H., Zhao, Y., & Zhao, J. (2017).. Nrf2 Inhibits NLRP3 Inflammasome Activation Through Regulating Trx1/TXNIP Complex in Cerebral Ischemia Reperfusion Injury. Behavioural Brain Research.

      16. Ueda, K., Masuda, A., Fukuda, M., Tanaka, S., Hosokawa, M., & Iwakawa, S. (2017). Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells. Drug Metabolism and Pharmacokinetics.
      17. Yang, Z., Zhu, M. L., Li, D. H., Zeng, R., & Han, B. N. (2017). N-Me-trichodermamide B isolated from Penicillium janthinellum, with antioxidant properties through Nrf2-mediated signaling pathway. Bioorganic & Medicinal Chemistry.
      18. Ding, C. H., Deng, L. F., Chen, F., Ding, K., Chen, W. S., Xie, W. F., & Zhang, X. (2017). p. Q511L mutation of HNF1α in hepatocellular carcinoma suppresses the transcriptional activity and the anti-tumor effect of HNF1α. Biochemical and Biophysical Research Communications.
      19. Zhang, F., Zhao, L., Wang, S., Yang, J., Lu, G., Luo, N., ... & Wei, W. (2017). Construction of a Biomimetic Magnetosome and Its Application as a SiRNA Carrier for High‐Performance Anticancer Therapy. Advanced Functional Materials.DOI: 10.1002/adfm.201703326.
      20. R Kawaguchi, N Hirata, Y Tokinaga,(2017).Nitrite administration improves sepsis-induced myocardial and mitochondrial dysfunction by modulating stress signal responses. Journal of Anesthesia ,23 Oct 2017, 31(6):885-894.DOI: 10.1007/s00540-017-2417-0
      21. Li Liu,Wei Wu, Jing Li, Wei-Hua Jiao,Li-Yun Liu ,Jie Tanga, Lei Liua, Fan Suna,Bing-Nan Hana,Hou-Wen Lin(2018).Two sesquiterpene aminoquinones protect against oxidative injury in HaCaT keratinocytes via activation of AMPKα/ERK-Nrf2/ARE/HO-1 signaling.Biomedecine & pharmacotherapie 100:417-425 · February 2018 .DOI: 10.1016/j.biopha.2018.02.034
      22. W Kang, L Shang, T Wang, H Liu, S Ge(2018).Rho-kinase Inhibitor Y-27632 Down-regulates LPS-induced IL-6 and IL-8 Production via Blocking p38 MAPK and NF-κB pathways in Human Gingival Fibroblasts.Journal of periodontology. 2018 Apr 6. doi: 10.1002/JPER.17-0571.
      23. Jianbin Mo ,Qingyun Xie, Wei Wei , Jing Zhao(2018).Revealing the immune perturbation of black phosphorus nanomaterials to macrophages by understanding the protein corona. NATURE COMMUNICATIONS | (2018) 9:2480 | DOI: 10.1038/s41467-018-04873-7.
      24. Liu Q, Zhao Y, Zheng L, Zhu X, Cui L, Cao Y(2018).The Glycosylphosphatidylinositol Transamidase Complex Subunit PbGPI16 of Plasmodium berghei Is Important for Inducing Experimental Cerebral Malaria.Infect Immun. 2018 Jul 23;86(8). doi: 10.1128/IAI.00929-17.
      25. Li et al.(2018).KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc.Journal of Experimental & Clinical Cancer Research .doi.org/10.1186/s13046-018-0861-9.
      26. Peng-Cheng Kang etal (2018).miR-191 Inhibition Induces Apoptosis Through Reactivating Secreted Frizzled-Related Protein-1 in Cholangiocarcinoma.Cell Physiol Biochem .doi.org/10.1159/000493654.
      27. Jiming Yin,et al (2018). Apelin inhibited epithelial−mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i. Cell Death & Disease.DOI 10.1038/s41419-018-1098-4.
      28. Hirofumi Sakurai,et al (2018).Sulforaphane ameliorates steroid insensitivity through an Nrf2-dependent pathway in cigarette smoke-exposed asthmatic mice.Free Radical Biology and Medicine. doi.org/10.1016/j.freeradbiomed.2018.10.400.
      29. Jiwei Hou etal (2018).M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis.Cell Communication and Signaling.doi.org/10.1186/s12964-018-0300-8
      30. Zhang C etal (2018).Knockdown of long non-coding RNA CCDC144NL-AS1 attenuates migration and invasion phenotypes in endometrial stromal cells from endometriosis.Biol Reprod. 2018 Nov 28. doi: 10.1093/biolre/ioy252.

      31. ShaoWei etal (2018).Overexpression of Toll-like receptor 4 enhances LPS-induced inflammatory response and inhibits Salmonella Typhimurium growth in ovine macrophages. European Journal of Cell Biology .DOI: 10.1016/j.ejcb.2018.11.004.
      32. T Otani etal (2018).Osteocalcin triggers Fas/FasL-mediated necroptosis in adipocytes via activation of p300.Cell Death & Disease. doi:10.1038/s41419-018-1257-7.
      33. Qi Qian etal (2018).Down-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer’s disease.FASEB Journal.doi: 10.1096/fj.201801846R.
      34. Rong Li etal (2018).Hyperbaric oxygen treatment promotes antioxidative effects on rats with acute carbon monoxide poisoning via NF-E2-related factor 2 activation.Int J Clin Exp Med.
      35. Bao, W., Liu, X., Lv, Y., Lu, G. H., Li, F., Zhang, F., ... & Li, Y. (2019). Nanolongan with Multiple On-Demand Conversions for Ferroptosis-Apoptosis Combined Anticancer Therapy. ACS Nano.DOI: 10.1021/acsnano.8b05602.
      36. Zhao W etal (2019).The role and molecular mechanism of Trop2 induced epithelial-mesenchymal transition through mediated β-catenin in gastric cancer.Cancer Medicine.DOI: 10.1002/cam4.1934.
      37. Zhou et al.ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma.Journal of Experimental & Clinical Cancer Research (2019) .doi.org/10.1186/s13046-018-1011-0.
      38. Li, P. C., Li, K., Wang, J., Zhao, C. Z., Zhao, S. Z., Hou, L., ... & Wang, X. J. (2019). The AAA-ATPase MIDASIN 1 Functions in Ribosome Biogenesis and Is Essential for Embryo and Root Development. Plant physiology, pp-01225.DOI:10.1104/pp.18.01225.
      39. Kong, P., Yu, Y., Wang, L., Dou, Y. Q., Zhang, X. H., Cui, Y., ... & Cui, W. (2019). circ-Sirt1 controls NF-κB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle cells. Nucleic Acids Research.Doi: 10.1093/nar/gkz141
      40. Fu, J., Li, G., Wu, X., & Zang, B. Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis. Inflammation, 1-11.DOI: 10.1007/s10753-019-00987-2
      41. Zhu, Y., Shao, Y., Qu, X., Guo, J., Yang, J., Zhou, Z., & Wang, S. (2019). Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway. Biochemical and Biophysical Research Communications.
      42. Sanada, T. J., Sakao, S., Naito, A., Ishibashi-Ueda, H., Suga, M., Shoji, H., ... & Ishida, K. (2019). Characterization of pulmonary intimal sarcoma cells isolated from a surgical specimen: In vitro and in vivo study. PloS one, 14(3), e0214654.
      43. Lin, W., Xu, L., Pan, Q., Lin, S., Feng, L., Wang, B., ... & Wang, Y. (2019). Lgr5-overexpressing mesenchymal stem cells augment fracture healing through regulation of Wnt/ERK signaling pathways and mitochondrial dynamics. The FASEB Journal, fj-201900082RR.doi: 10.1096/fj.201900082RR.
      44. Liu, B., Gu, Y., Pei, S., Peng, Y., Chen, J., Pham, L. V., ... & Wang, H. (2019). Interleukin-1 receptor associated kinase (IRAK)-M-mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE). Journal of Autoimmunity.doi.org/10.1016/j.jaut.2019.04.020
      45. Zhang, X., Cao, X., Dang, M., Wang, H., Chen, B., Du, F., ... & Guo, C. (2019). Soluble receptor for advanced glycation end-products enhanced the production of IFN-γ through the NF-κB pathway in macrophages recruited by ischemia/reperfusion. International journal of molecular medicine, 43(6), 2507-2515.DOI: 10.3892/ijmm.2019.4152
      46. Li, M., Zhang, H., Liu, H., Tian, H., Tang, X., Bai, Y., & Wang, W. (2019). Abnormal expression of TBX4 during anorectal development in rat embryos with ethylenethiourea-induced anorectal malformations. Biological Research,52(1), 27.doi.org/10.1186/s40659-019-0235-6

      47. Huang, C., Chen, Y., Dai, H., Zhang, H., Xie, M., Zhang, H., ... & Chen, Z. (2019). UBAP2L arginine methylation by PRMT1 modulates stress granule assembly. Cell Death & Differentiation, 1.doi.org/10.1038/s41418-019-0350-5
      48. Kang, Y., Li, Y., Zhang, T., Chi, Y., & Liu, M. Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes. International Journal of Molecular Medicine.DOI: 10.3892/ijmm.2019.4209
      49. Ren, R. C., Wang, L. L., Zhang, L., Zhao, Y. J., Wu, J. W., Wei, Y. M., ... & Zhao, X. Y. DEK43 is a P‐type PPR Protein Responsible for the Cis‐splicing of nad4 in Maize Mitochondria. Journal of Integrative Plant Biology.doi: 10.1111/jipb.12843.
      50. Zhu, W., Xu, R., Du, J., Fu, Y., Li, S., Zhang, P., ... & Jiang, H. (2019). Zoledronic acid promotes TLR-4–mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw. The FASEB Journal, 33(4), 5208-5219.doi: 10.1096/fj.201801791RR
      51. Ye, M., Ma, J., Liu, B., Liu, X., Ma, D., & Dong, K. Linc01105 acts as an oncogene in the development of neuroblastoma. Oncology Reports.doi.org/10.3892/or.2019.7257
      52. Sun, L. J., Qiao, W., Xiao, Y. J., Cui, L., Wang, X., & Ren, W. D. (2019). Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway. International Immunopharmacology, 75, 105782.doi.org/10.1016/j.intimp.2019.105782
      53. Diao, H., Cheng, N., Zhao, Y., Xu, H., Dong, H., Thamm, D. H., ... & Lin, D. (2019). Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling. BMC Veterinary Research, 15(1), 1-10.doi.org/10.1186/s12917-019-2026-2
      54. Li Q et al (2019).Porphyromonas gingivalis degrades integrin β1 and induces AIF-mediated apoptosis of epithelial cells.Infect Dis (Lond). 2019 Aug 14:1-9. doi: 10.1080/23744235.2019.1653490.
      55. Tong, S. M., Wang, D. Y., Gao, B. J., Ying, S. H., & Feng, M. G. The DUF1996 and WSC domain‐containing protein Wsc1I acts as a novel sensor of multiple stress cues in Beauveria bassiana. Cellular Microbiology, e13100.DOI: 10.1111/cmi.13100
      56. Cao, H., Chen, X., Hou, J., Wang, C., Xiang, Z., Shen, Y., & Han, X. (2019). The Shh/Gli signaling cascade regulates myofibroblastic activation of lung-resident mesenchymal stem cells via the modulation of Wnt10a expression during pulmonary fibrogenesis. Laboratory Investigation, 1-15.
      57. Liu, L., Zhu, H., Wu, W., Shen, Y., Lin, X., Wu, Y., ... & Lin, H. W. (2019). Neoantimycin F, a Streptomyces-Derived Natural Product Induces Mitochondria-Related Apoptotic Death in Human Non-Small Cell Lung Cancer Cells. Frontiers in Pharmacology, 10.
      58. Zhang, Y., Xie, H., Tang, W., Zeng, X., Lin, Y., Xu, L., ... & Yuan, D. (2019). Trichostatin A, a histone deacetylase inhibitor, alleviates eosinophilic meningitis induced by Angiostrongylus cantonensis infection in mice. Frontiers in Microbiology, 10.
      59. Li, J. L., Wang, J. P., Chang, H., Deng, S. M., Du, J. H., Wang, X. X., ... & Song, Y. H. (2019). FEN1 inhibitor increases sensitivity of radiotherapy in cervical cancer cells. Cancer medicine.doi.org/10.1002/cam4.2615
      60. Wang, T., Du, Q., Niu, Y., Zhang, X., Wang, Z., Wu, X., ... & Huang, Y. (2019). Cellular p32 Is a Critical Regulator of Porcine Circovirus Type 2 Nuclear Egress. Journal of virology, 93(23).DOI: 10.1128/JVI.00979-19
      61. Wang, T., Duan, Y. M., Fu, Q., Liu, T., Yu, J. C., Sui, Z. Y., ... & Wen, G. Q. (2019). IM-12 activates the Wnt–β-catenin signaling pathway and attenuates rtPA-induced hemorrhagic transformation in rats after acute ischemic stroke. Biochemistry and Cell Biology, (999)

      62. Du, Y., Du, Y., Zhang, Y., Huang, Z., Fu, M., Li, J., ... & He, G. (2019). MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer’s disease models. Signal Transduction and Targeted Therapy, 4(1), 1-12.
      63. Xie, X., Yu, C., Ren, Q., Wen, Q., Zhao, C., Tang, Y., & Du, Y. (2019). Exposure to HBCD promotes adipogenesis both in vitro and in vivo by interfering with Wnt6 expression. Science of The Total Environment, 135917.
      64. Jiang, H., Li, R., Zhang, Z., Chang, C., Liu, Y., Liu, Z., ... & Wang, Q. Retinoid X receptor α (RXRα)‐mediated erythroid‐2‐related factor‐2 (NRF2) inactivation contributes to N, N‐dimethylformamide (DMF)‐induced oxidative stress in HL‐7702 and HuH6 cells. Journal of Applied Toxicology.
      65. Dou, Y. Q., Kong, P., Li, C. L., Sun, H. X., Li, W. W., Yu, Y., ... & Dong, C. (2020). Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia. Theranostics, 10(3), 1197. Dou, Y. Q., Kong, P., Li, C. L., Sun, H. X., Li, W. W., Yu, Y., ... & Dong, C. (2020). Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia. Theranostics, 10(3), 1197
      66. Li, C. L., Liu, B., Wang, Z. Y., Xie, F., Qiao, W., Cheng, J., ... & Liu, D. S. (2020). Salvianolic acid B improves myocardial function in diabetic cardiomyopathy by suppressing IGFBP3. Journal of Molecular and Cellular Cardiology.
      67. Sakata, J., Hirosue, A., Yoshida, R., Matsuoka, Y., Kawahara, K., Arita, H., ... & Gohara, S. (2020). Enhanced Expression of IGFBP-3 Reduces Radiosensitivity and Is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma. Cancers, 12(2), 494.
      68. Du, X., He, W., He, H., & Wang, H. (2020). Beta-catenin inhibits bovine parainfluenza virus type 3 replication via innate immunity pathway. BMC Veterinary Research, 16(1), 1-10.
      69. Li, C. L., Liu, X. H., Qiao, Y., Ning, L. N., Li, W. J., Sun, Y. S., ... & Ma, C. M. (2020). Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway. European Journal of Pharmacology, 173052.
      70. Tong, S. M., Wang, D. Y., Cai, Q., Ying, S. H., & Feng, M. G. (2020). Opposite Nuclear Dynamics of Two FRH-Dominated Frequency Proteins Orchestrate Non-Rhythmic Conidiation in Beauveria bassiana. Cells, 9(3), 626.
      71. Tang, S. Y., Liu, D. X., Li, Y., Wang, K. J., Wang, X. F., Su, Z. K., ... & Chen, Y. H. (2020). Caspr1 Facilitates sAPPα Production by Regulating α-Secretase ADAM9 in Brain Endothelial Cells. Frontiers in Molecular Neuroscience, 13, 23.
      72. Wei, R., Bao, W., He, F., Meng, F., Liang, H., & Luo, B. (2020). Pannexin1 channel inhibitor (10panx) protects against transient focal cerebral ischemic injury by inhibiting RIP3 expression and inflammatory response in rats. Neuroscience.
      73. Duan, Y., Wang, Z., Xu, L., Sun, L., Song, H., Yin, H., & He, F. (2020). lncRNA SNHG3 acts as a novel Tumor Suppressor and regulates Tumor Proliferation and Metastasis via AKT/mTOR/ERK pathway in Papillary Thyroid Carcinoma. Journal of Cancer, 11(12), 3492-3501.
      74. Hua, Q., Mi, B., Xu, F., Wen, J., Zhao, L., Liu, J., & Huang, G. (2020). Hypoxia-induced lncRNA-AC020978 promotes proliferation and glycolytic metabolism of non-small cell lung cancer by regulating PKM2/HIF-1α axis. Theranostics, 10(11), 4762.
      75. Duan, C., Kuang, L., Xiang, X., Zhang, J., Zhu, Y., Wu, Y., ... & Li, T. (2020). Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH-pathways. Cell Death & Disease, 11(4), 1-19.

      76. Ren, L., Zhou, T., Wang, Y., Wu, Y., Xu, H., Liu, J., ... & Li, X. (2020). RNF8 induces β-catenin-mediated c-Myc expression and promotes colon cancer proliferation. J. Biol. Sci, 16(12), 2051-2062.

      77. Hu, B., Wei, H., Song, Y., Chen, M., Fan, Z., Qiu, R., ... & Wang, F. (2020). NF-κB and Keap1 Interaction Represses Nrf2-Mediated Antioxidant Response in Rabbit Hemorrhagic Disease Virus Infection. Journal of Virology, 94(10).

      78. Chen, Q., Xu, H., Zhu, J., Feng, K., & Hu, C. (2020). LncRNA MCM3AP-AS1 promotes breast cancer progression via modulating miR-28-5p/CENPF axis. Biomedicine & Pharmacotherapy, 128, 110289.

      79. Hu, W., Wu, X., Yu, D., Zhao, L., Zhu, X., Li, X., ... & Xu, Y. (2020). Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats. Experimental Neurology, 113374.

      80. Yu, H., Wu, Z., Wang, X., Gao, C., Liu, R., Kang, F., & Dai, M. Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation. International Journal of Oncology.

      81.Si, Y., Huang, J., Li, X., Fu, Y., Xu, R., Du, Y., ... & Jiang, H. (2020). AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations. Cell Communication and Signaling, 18(1), 1-13.

      82. Yuan, H. X., Chen, C. Y., Li, Y. Q., Ning, D. S., Li, Y., Chen, Y. T., ... & Jian, Y. P. (2020). Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine. American Journal of Physiology-Endocrinology and Metabolism.

      83. Dang, H., Chen, L., Tang, P., Cai, X., Zhang, W., Zhang, R., ... & Tang, H. (2020). LINC01419 promotes cell proliferation and metastasis in hepatocellular carcinoma by enhancing NDRG1 promoter activity. Cellular Oncology, 1-17.

      84. Wang, H., Xu, P., Luo, X., Hu, M., Liu, Y., Yang, Y., ... & Wu, Y. (2020). Phosphorylation of YAP Impairs Trophoblast Invasion and Migration: Implications for the Pathogenesis of Fetal Growth Restriction. Biology of Reproduction.

      85. Shen, X., Zhang, Y., Lin, C., Weng, C., Wang, Y., Feng, S., ... & Wang, H. Calcineurin inhibitors ameliorate PAN‐induced podocyte injury through the NFAT‐Angptl4 pathway. The Journal of Pathology.

      86. Zhu, B., Wu, G., Wang, C., Xiao, Y., Jin, J., Wang, K., ... & Xia, Z. (2020). Soluble cluster of differentiation 74 regulates lung inflammation through the nuclear factor-κB signaling pathway. Immunobiology, 152007.

      87. Wang, Y., Zhao, M., Cui, J., Wu, X., Li, Y., Wu, W., & Zhang, X. (2020). Ochratoxin A induces reprogramming of glucose metabolism by switching energy metabolism from oxidative phosphorylation to glycolysis in human gastric epithelium GES-1 cells in vitro. Toxicology Letters.

      88.Jiang T, Yang W, Zhang H,Song Z, Liu T and Lv X (2020) Hydrogen Sulfide Ameliorates Lung Ischemia-Reperfusion Injury Through SIRT1 Signaling Pathway in Type 2 Diabetic Rats. Front. Physiol. 11:596.doi: 10.3389/fphys.2020.00596

      89.Zheng, X. H., Wang, L. L., Zheng, M. Z., Zhong, J. J., Chen, Y. Y., & Shen, Y. L. (2020). RGFP966 inactivation of the YAP pathway attenuates cardiac dysfunction induced by prolonged hypothermic preservation.Journal of Zhejiang University-SCIENCE B,21(9), 703-715.

      90.Wang, J., Bao, J., Zhou, B., Li, M., Li, X., & Jin, J. The osa‐miR164 target OsCUC1 functions redundantly with OsCUC3 in controlling rice meristem/organ boundary specification.New Phytologist.

      91.Chen, Y., Jiang, T., Zhang, H., Gou, X., Han, C., Wang, J., ... & Jing, X. (2020). LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.Nature Cell Biology,22(10), 1276-1285.

      92.Y Sun, J Huang, Y Chen, H Shang, W Zhang, J Yu.(2020).Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease.Bioorganic Chemistry

      93.Ye, Mujie, et al. "Downregulation of MEG3 promotes neuroblastoma development through FOXO1-mediated autophagy and mTOR-mediated epithelial-mesenchymal transition." International Journal of Biological Sciences15 (2020): 3050-3061.

      94.Zhou, H., Hu, X., Li, N., Li, G., Sun, X., Ge, F., ... & Yang, L. Loganetin and 5‐fluorouracil synergistically inhibit the carcinogenesis of gastric cancer cells via down‐regulation of the Wnt/β‐catenin pathway. Journal of Cellular and Molecular Medicine.

      95.Song, H., Li, H., Ding, X., Li, M., Shen, H., Li, Y., ... & Xing, L. Long non‑coding RNA FEZF1‑AS1 facilitates non‑small cell lung cancer progression via the ITGA11/miR‑516b‑5p axis. International Journal of Oncology.

      96.Li, J., Liao, T., Liu, H., Yuan, H., Ouyang, T., Wang, J., ... & Zhao, H. (2020). Hypoxic glioma stem cell-derived exosomes containing Linc01060 promote progression of glioma by regulating the MZF1/c-Myc/HIF-1α. Cancer Research.

      97.Zhang, X., Lin, X., Qin, C., Huang, K., Sun, X., Zhao, L., & Jin, M. (2020). Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins. Frontiers in Microbiology, 11.

      98.Yang, W., Liu, J., Hou, L., Chen, Q., & Liu, Y. (2020). Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line. Life Sciences, 118796.

      99.Deng, X., Lin, N., Fu, J., Xu, L., Luo, H., Jin, Y., ... & Su, J. (2020). The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer. Oxidative Medicine and Cellular Longevity, 2020.

      100.Zhou, M., Hu, H., Han, Y., Li, J., Zhang, Y., Tang, S., ... & Zhang, X. (2020). Long non‐coding RNA 01126 promotes periodontitis pathogenesis of human periodontal ligament cells via miR‐518a‐5p/HIF‐1α/MAPK pathway. Cell Proliferation, e12957.

      101.Zhang, X., Yuan, H., Zhang, S., Zhang, S., Zhao, L., Gao, H., ... & Liu, Y. (2020). A polypeptide D-TTK001 targeting HBx controls cccDNA against HBV.

      102.Li, J., Chen, D., Zhang, X., Yu, T., Zhao, F., Geng, Q., ... & Zhu, M. (2020). Nuclear Export Protein CSE1L Interacts with P65 and Promotes NSCLC Growth via NF-κB/MAPK Pathway.

      103.Huang, H., Zhu, X., Cheng, H., Kuang, X., Long, C., Deng, X., ... & Shen, H. 2, 3, 5, 6-Tetramethylpyrazine protects retinal photoreceptors against endoplasmic reticulum stress by modulating ATF4-mediated inhibition of PRP aggregation. Journal of Molecular Medicine, 1-20.

      104.Liu, Y., Sun, Y., Huang, Y., Cheng, K., Xu, Y., Tian, Q., & Zhang, S. CHIP promotes Wnt signaling and regulates Arc stability by recruiting and polyubiquitinating LEF1 or Arc. Cell Death Discovery, 7(1), 1-12.

      105.Li, Y., Sun, C., Tan, Y., Zhang, H., Li, Y., & Zou, H. (2021). ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition. International Journal of Biological Sciences, 17(2), 635-650/

      106.Xu, Y., Wu, X., Hu, W., Yu, D., Shao, Z., Li, W., ... & Lv, K. (2021). RIP3 facilitates necroptosis through CaMKII and AIF after intracerebral hemorrhage in mice. Neuroscience Letters, 135699.

      107.Song, C., & Zhou, C. (2021). HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.Journal of Experimental & Clinical Cancer Research,40(1), 1-16.

      108.Nakajima, M., Matsuyama, M., Kawaguchi, M., Kiwamoto, T., Matsuno, Y., Morishima, Y., ... & Hizawa, N. (2021). Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions.mBio,12(1).

      109.Blondel-Tepaz, E., Leverve, M., Sokrat, B. et al. The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis. Oncogene (2021).

      110.Dai, C., Wu, B., Chen, Y. et al. Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage. Cell Death Differ (2021). https://doi.org/10.1038/s41418-021-00757-4

      111.Lv, H. W., Xing, W. Q., Ba, Y. F., Li, H. M., Wang, H. R., & Li, Y. (2021). SMYD3 confers cisplatin chemoresistance of NSCLC cells in an ANKHD1-dependent manner. Translational Oncology, 14(6), 101075.

      112.Ke, Q., Yang, J., Liu, H., Huang, Z., Bu, L., Jin, D., & Liu, C. (2021). Dose-and time-effects responses of Nonylphenol on oxidative stress in rat through the Keap1-Nrf2 signaling pathway. Ecotoxicology and Environmental Safety, 216, 112185.

      113.Zheng, Y., Kou, J., Wang, P., Ye, T., Wang, Z., Gao, Z., ... & Yang, L. (2021). Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages. Aging (Albany NY), 13(5), 7096.

      114.Tian, Z., Bao, W., Liu, M., Meng, J., Liu, S., Wang, S., ... & Wei, W. (2021). MOF-Based Nanoagent Enables NIR-Triggered Dual Damage to Mitochondria via Synergistically Reinforced Oxidative Stress and Calcium Overload.

      115.Cao, L., Xu, C., Yi, P., Li, H., Lin, Y., Cai, G., ... & Chen, J. (2021). Asparaginyl endopeptidase (AEP) regulates myocardial apoptosis in response to radiation exposure via alterations in NRF2 activation. American Journal of Cancer Research, 11(4), 1206.

      116.Liu, Yf., Zhang, L., Wu, Q. et al. Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway. Acta Pharmacol Sin (2021). https://doi.org/10.1038/s41401-021-00671-y

      117.Gao, C., Jia, W., Xu, W., Wu, Q., & Wu, J. (2021). Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke. Journal of Neuroinflammation, 18(1), 1-16.

      118.Weize Sun, Yao Jian, Mengxue Zhou, Yishan Yao, Na Tian, Chao Li, Jun Chen, Xuesong Wang, and Qianxiong Zhou.(2021).Selective and Efficient Photoinactivation of Intracellular Staphylococcus aureus and MRSA with Little Accumulation of Drug Resistance: Application of a Ru(II) Complex with Photolabile Ligands.Journal of Medicinal Chemistry Article ASAP.DOI: 10.1021/acs.jmedchem.0c02257

      119.L. Zhang, L. Xu, H. Chen, W. Zhang, C. Xing, Z. Qu, J. Yu, C. Zhuang,Structure-based molecular hybridization design of Keap1-Nrf2 inhibitors as novel protective agents of acute lung injury, European Journal of Medicinal Chemistry, https://doi.org/10.1016/j.ejmech.2021.113599.

      120.Zeng, S., Chen, L., Sun, Q., Zhao, H., Yang, H., Ren, S., ... & Xu, H. (2021). Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade. European Journal of Pharmacology, 174253.

      121.Zhang, Z., Li, Z., Ma, Z., Deng, M., Xing, M., Wu, J., ... & Zou, W. (2021). Annexin A3 as a Marker Protein for Microglia in the Central Nervous System of Rats. Neural Plasticity, 2021.

      122.Jing Xie; Yonggang Fan; Rongjun Jia; Fan Yang; Liman Ma; Lihua Li.(2021).Yes‐associated protein regulates the hepatoprotective effect of vitamin D receptor activation through promoting adaptive bile duct remodeling in cholestatic mice.The Journal of Pathology.https://doi.org/10.1002/path.5750.

      123.Thirstrup, D. J., Yao, J., Sherman, J., Mueller, I. A., & Wiegraebe, W. (2021). Mapping Protein Numbers in Living Cells.bioRxiv.

      124.Zhang, X. Y., Tang, H., Liu, Y., Du, N., Tian, S., & Dou, Y. Q. (2021). circYap inhibits oral squamous cell carcinoma by arresting cell cycle. Acta Odontologica Scandinavica, 1-8.

      125.Han Y, Yang Q, Huang Y, et al.Mechanical force inhibited hPDLSCs proliferation with the downregulation of MIR31HG via DNA methylation. Oral Dis.2020;00:1–15. https://doi.org/10.1111/odi.13637

      126.Zhang, J. Y., Zhu, W. W., Wang, M. Y., Zhai, R. D., Wang, Q., Shen, W. L., & Liu, L. K. (2021). Cancer-Associated Fibroblasts Promote Oral Squamous Cell Carcinoma Progression Through LOX-Mediated Matrix Stiffness.Journal of Translational Medicine, 19(1), 1-16.

      127.Liu, W., Zhang, N., Du, Y., Liu, X., Ma, J., & Yan, L. (2021). 6-(7-nitro-2, 1, 3-benzoxadiazol-4-ylthio) hexanol ameliorates the progression of endometriosis by regulating GSTM4 expression to inhibit proliferation and induce apoptosis.

      128.Liu, Y., Sun, Y., Han, S., Guo, Y., Tian, Q., Ma, Q., & Zhang, S. (2021). CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1. Cell Death Discovery, 7(1), 1-8.

      129.Wang, Y., Ma, G., Wang, X. F., Na, L., Guo, X., Zhang, J., ... & Wang, X. (2022). Keap1 recognizes EIAV early accessory protein Rev to promote antiviral defense. PLoS pathogens, 18(2), e1009986.

      130.Lu, L., Shi, Y., Zhu, D., Liu, J., Zhang, T., Li, W., ... & Sun, M. (2021). Attenuated Function of Angiotensin-(1-7) in Placental Artery During Preeclampsia not through MAS1 Receptor.

      131.Duan, C., Kuang, L., Hong, C., Xiang, X., Liu, J., Li, Q., ... & Li, T. (2021). Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2. Cell Death & Disease, 12(11), 1-10.

      132.Bao, W., Liu, M., Meng, J., Liu, S., Wang, S., Jia, R., ... & Tian, Z. (2021). MOFs-based nanoagent enables dual mitochondrial damage in synergistic antitumor therapy via oxidative stress and calcium overload. Nature Communications, 12(1), 1-17.

      133.Chen, Y., Qin, H., Yue, X., Zhou, J., Liu, L., Nie, Y., & Ye, M. (2021). Highly Efficient Enrichment of O-GlcNAc Glycopeptides Based on Chemical Oxidation and Reversible Hydrazide Chemistry. Analytical Chemistry.

      134.Nakajo, T., Katayoshi, T., Kitajima, N., & Tsuji-Naito, K. (2021). 1, 25-Dihydroxyvitamin D3 attenuates IL-1β secretion by suppressing NLRP1 inflammasome activation by upregulating the NRF2-HO-1 pathway in epidermal keratinocytes. Redox Biology, 102203.

      135.Wang, X. W., Guo, Q. Q., Yu, Y., Zhou, T. T., Zhang, S. Y., Wang, Z., ... & Cao, L. (2021). The deacetylation of Foxk2 by Sirt1 reduces chemosensitivity to cisplatin. Journal of cellular and molecular medicine.

      136.Tang, T. P., Qin, C. X., & Yu, H. (2021). MCM3AP-AS1 regulates proliferation, apoptosis, migration, and invasion of breast cancer cells via binding with ZFP36. Translational Cancer Research, 10(10).

      137.Yamana, K., Inoue, J., Yoshida, R., Sakata, J., Nakashima, H., Arita, H., ... & Nakayama, H. (2021). Extracellular vesicles derived from radioresistant oral squamous cell carcinoma cells contribute to the acquisition of radioresistance via the miR‐503‐3p‐BAK axis. Journal of Extracellular Vesicles, 10(14), e12169.

      138.Jin-xia Liu, Dong-yue Ma, Xin-yu Zhi, Ming-wu Wang, Jiang-yue Zhao, Yu Qin.(2021).MiR-125b attenuates retinal pigment epithelium oxidative damage via targeting Nrf2/HIF-1α signal pathway,Experimental Cell Research.

      139.Lu, F., Song, Y., Cui, S., Zhao, H., Chen, Y., & Du, H. (2021). LncRNA MIAT promotes the proliferation, migration, and invasion of melanoma cells through recruiting TCF12 and activating NFAT5. American Journal of Translational Research, 13(11), 12588.

      140.Liu H, Huang Y, Yang Y,Han Y, Jia L, Li W. Compressive force-induced LincRNA-p21 inhibits mineralization of
      cementoblasts by impeding autophagy. FASEB J.2022;36:e22120. doi:10.1096/fj.20210 1589R

      141.Ma G, Chen F, Liu Y,et al. Nur77 ameliorates age-related renal tubulointerstitial fibrosis by suppressing the TGF-β/
      Smads signaling pathway. FASEB J.2022;36:e22124. doi:10.1096/fj.20210 1332R

      142.Deng, M., Zhang, Z., Xing, M., Liang, X., Li, Z., Wu, J., Jiang, S., Weng, Y.,Guo, Q., Zou, W., LncRNA MRAK159688 facilitates morphine tolerance by promoting REST-mediated inhibition of mu opioid receptor in rats, Neuropharmacology (2022), doi: https://doi.org/10.1016/j.neuropharm.2021.108938.

      143.Stofkova, A., Zloh, M., Andreanska, D., Fiserova, I., Kubovciak, J., Hejda, J., ... & Murakami, M. (2022). Depletion of Retinal Dopaminergic Activity in a Mouse Model of Rod Dysfunction Exacerbates Experimental Autoimmune Uveoretinitis: A Role for the Gateway Reflex. International Journal of Molecular Sciences, 23(1), 453.

      144.Huang, M., Dong, Y., Sun, G., & Yu, Y. (2022). Circ‐Sirt1 inhibits vascular smooth muscle cells proliferation via the c‐Myc/cyclin B1 axis. Cell Biology International.

      145.Shen, M., Zhang, R., Jia, W., Zhu, Z., Zhao, L., Huang, G., & Liu, J. (2022). RNA-binding protein p54nrb/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer. Cell Death & Disease, 13(1), 1-14.

      146.Ogata, R., Mori, S., Ohmori, H., Kishi, S., Fujiwara-Tani, R., Sasaki, T., ... & Kuniyasu, H. (2022). Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer. Oncotarget, 13, 122.

      147.Shenjia Huang, Linsheng Liu, Xiaoxue Liu, Lin Song, Chenrong Huang, Liyan Miao.(2022).Development and application of a rapid and sensitive liquid chromatography-mass spectrometry method for simultaneous analysis of cytarabine, cytarabine monophosphate, cytarabine diphosphate and cytarabine triphosphate in the cytosol and nucleus,Journal of Pharmaceutical and Biomedical Analysis.

      148.Xiaoyu Kong, Huacai Wang, Mengting Zhang, Xiaoying Chen, Rongxiang Fang, Yongsheng Yan.(2022).A SA-regulated lincRNA promotes Arabidopsis disease resistance by modulating pre-rRNA processing,Plant Science.

      149.Li-Jun Liang; Yan-Fei Zhang; Di Wang; Fu-Ying Wang; Da-Wei Xie; et al.(2022). Oncoprotein CIP2A controls PKM2 dimer-tetramer transition through phosphorylation of serine 287 in non-small cell lung cancer.

      150.Zeng, S., Tan, L., Sun, Q., Chen, L., Zhao, H., Liu, M., ... & Xu, H. (2022). Suppression of colitis-associated colorectal cancer by scutellarin through inhibiting Hedgehog signaling pathway activity. Phytomedicine, 153972.

      151.Zhao, J. L., Ye, Y. C., Gao, C. C., Wang, L., Ren, K. X., Jiang, R., ... & Qin, H. Y. (2022). Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis. Cell Reports, 38(10), 110451.

      152.Zhang, W., Liao, Y., Lou, J., Zhuang, M., Yan, H., Li, Q., ... & Sun, Y. (2022). CircRNA_Maml2 promotes the proliferation and migration of intestinal epithelial cells after severe burns by regulating the miR-93-3p/FZD7/Wnt/β-catenin pathway. Burns & Trauma, 10.

      153.Wang, M., Qi, Y., Cao, Y., Zhang, X., Wang, Y., Zhang, J., ... & Han, H. (2022). Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat generated by CRISPR/Cas9. bioRxiv.

      154.Pan, R., Zhang, Z., Jia, H., Ma, J., Wu, C., Xue, P., ... & Sun, J. (2022). CAMTA1–PPP3CA–NFATc4 multi-protein complex mediates the resistance of colorectal cancer to oxaliplatin. Cell Death Discovery, 8(1), 1-13.

      155.Han, Y., Yang, Q., Huang, Y., Jia, L., Zheng, Y., & Li, W. (2022). Long non-coding RNA SNHG5 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the miR-212-3p/GDF5/SMAD pathway. Stem Cell Research & Therapy, 13(1), 1-20.

      156.Chen, D., Zhou, H., Cai, Z., Cai, K., Liu, J., Wang, W., ... & Wen, Z. (2022). CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling. Journal of Experimental & Clinical Cancer Research, 41(1), 1-23.

      157.Yang, X., Sun, W., Jing, X., Zhang, Q., Huang, H., & Xu, Z. (2022). C/EBP homologous protein promotes Sonic Hedgehog secretion from type II alveolar epithelial cells and activates Hedgehog signaling pathway of fibroblast in pulmonary fibrosis. Respiratory Research, 23(1), 1-16.

      158.Matsuoka, Y., Yoshida, R., Kawahara, K., Sakata, J., Arita, H., Nkashima, H., ... & Nakayama, H. (2022). The antioxidative stress regulator Nrf2 potentiates radioresistance of oral squamous cell carcinoma accompanied with metabolic modulation. Laboratory Investigation, 1-12.

      159.Yin, S., Song, R., Ma, J., Liu, C., Wu, Z., Cao, G., ... & Wang, Y. (2022). Receptor activity‐modifying protein 1 regulates mouse skin fibroblast proliferation via the Gαi3-PKA-CREB-YAP axis. Cell Communication and Signaling, 20(1), 1-18.

      160.Tanaka, S., Hosokawa, M., Tatsumi, A., Asaumi, S., Imai, R., & Ogawara, K. I. (2022). Improvement of resistance to oxaliplatin by vorinostat in human colorectal cancer cells through inhibition of Nrf2 nuclear translocation. Biochemical and Biophysical Research Communications, 607, 9-14.

      161.Liu Y, Song Y, CaoM,et al. A novel EHD1/CD44/Hippo/SP1 positive feedback loop potentiates stemness and metastasis
      in lung adenocarcinoma. Clin Transl Med.2022;12:e836. https://doi.org/10.1002/ctm2.836

      162.Zhang, J., Han, X., Chang, J.et al. Soluble RAGE attenuates myocardial I/R injuries via FoxO3–Bnip3 pathway.Cell. Mol. Life Sci.79,269 (2022). https://doi.org/10.1007/s00018-022-04307-0

      163.Shang, Q., Du, H., Wu, X., Guo, Q., Zhang, F., Gong, Z., ... & Kong, Y. (2022). FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma. Journal of Experimental & Clinical Cancer Research, 41(1), 1-18.

      164.Chen, Y., Zhu, L., Meng, H., Sun, X., & Xue, C. (2022). Ferulic Acid Protects Human Lens Epithelial Cells against Ionizing Radiation-Induced Oxidative Damage by Activating Nrf2/HO-1 Signal Pathway. Oxidative Medicine and Cellular Longevity, 2022.

      165.Peipei Ding, Yanqing Xu, Luying Li, Xinyue Lv, Ling Li, Jianfeng Chen, Danlei Zhou, Xiaochao Wang, Qi Wang, Wei Zhang, Tian Liao, Qing-Hai Ji, Qun-Ying Lei, Weiguo Hu(2022).Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis,Cell Reports,Volume 39, Issue 9

      166.Wang, S., Zhang, Z., Wang, J.et al. Neuronal GPER Participates in Genistein-Mediated Neuroprotection in Ischemic Stroke by Inhibiting NLRP3 Inflammasome Activation in Ovariectomized Female Mice.Mol Neurobiol (2022). https://doi.org/10.1007/s12035-022-02894-4

      167.Yousef, M. H., Salama, M., El-Fawal, H. A., & Abdelnaser, A. (2022). Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response. Molecular Neurobiology, 1-21.

      168.Lv, J., Fang, M., Sun, S., Wang, G., Fu, S., Sun, B., & Tong, J. (2022). Blockade of the Arid5a/IL-6/STAT3 axis underlies the anti-inflammatory effect of Rbpjl in acute pancreatitis. Cell & bioscience, 12(1), 1-18.

      169.Yang, X., Sun, W., Jing, X., Zhang, Q., Huang, H., & Xu, Z. (2022). Endoplasmic reticulum stress modulates the fate of lung resident mesenchymal stem cell to myofibroblast via C/EBP homologous protein during pulmonary fibrosis. Stem Cell Research & Therapy, 13(1), 1-18.

      170.Dai, Y., Huang, J., Kuang, P., Hu, Y., Zeng, Q., Zhang, W., ... & Liu, T. (2022). Dasatinib and interferon alpha synergistically induce pyroptosis-like cell death in philadelphia chromosome positive acute lymphoblastic leukemia. American Journal of Cancer Research, 12(6), 2817.

      171.Peng, T., Qiu, X., Tan, L., Yu, S., Yang, B., Dai, J., ... & Ding, C. (2022). Ubiquitination on Lysine 247 of Newcastle Disease Virus Matrix Protein Enhances Viral Replication and Virulence by Driving Nuclear-Cytoplasmic Trafficking. Journal of Virology, 96(2), e01629-21.

      172.Wu X, Zhen H, Liu Y, Li L, Luo Y, Liu X,Li S, Hao Z, Li M, Hu L, Qiao L and Wang J (2022) Tissue-Specific Expression of Circ_015343 and Its Inhibitory Effect on Mammary Epithelial Cells in Sheep. Front. doi:10.3389/fvets.2022.919162

      173.Yang, Q., Liu, P., Han, Y., Wang, C., Huang, Y., Li, X., ... & Li, W. (2022). Long noncoding RNA GAS5 alleviates the inflammatory response of human periodontal ligament stem cells by regulating the NF-κB signalling pathway. European Journal of Orthodontics.

      174.Zloh, M., Kutilek, P., & Stofkova, A. (2022). High-Contrast Stimulation Potentiates the Neurotrophic Properties of Müller Cells and Suppresses Their Pro-Inflammatory Phenotype. International Journal of Molecular Sciences, 23(15), 8615.

      175.Wang, R., Wang, J., Chen, Y.et al. Circular RNA circLDLR facilitates cancer progression by altering the miR-30a-3p/SOAT1 axis in colorectal cancer.Cell Death Discov.8,314 (2022). https://doi.org/10.1038/s41420-022-01110-5

      176.Liu, Y., Chen, Y., Ding, C., Zhu, X., Song, X., Ren, Y., ... & Sun, X. (2022). TRIM56 positively regulates TNFα-induced NF-κB signaling by enhancing the ubiquitination of TAK1. International Journal of Biological Macromolecules.

      177.Kishi, S., Fujiwara‐Tani, R., Honoki, K., Sasaki, R., Mori, S., Ohmori, H., ... & Kuniyasu, H. (2022). Oxidized high mobility group B‐1 enhances metastability of colorectal cancer via modification of mesenchymal stem/stromal cells. Cancer Science, 113(8), 2904.

      178.Lu, Y., Li, B., Xu, A., Liang, X., Xu, T., Jin, H., ... & Zeng, J. (2022). NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes. Frontiers in Molecular Neuroscience, 15.

      179.Shi-Kai Cao, Rui Liu, Miaodi Wang, Feng Sun, Aqib Sayyed, Hong Shi, Xiaomin Wang, Bao-Cai Tan, The small PPR protein SPR2 interacts with PPR-SMR1 to facilitate the splicing of introns in maize mitochondria, Plant Physiology, 2022;, kiac379, https://doi.org/10.1093/plphys/kiac379

      180.Huanhuan Teng; Yi Zhang; Chuanshan Jin; Tongsheng Wang; Shengzhuo Huang; et al.(2022).Polysaccharides from steam‐processed Polygonatum cyrtonema Hua protect against D‐galactose‐induced oxidative damage in mice via activation of Nrf2/ HO ‐1 signaling.Journal of the Science of Food and Agriculture.https://doi.org/10.1002/jsfa.12189

      181.Li, X., Gao, X., Yuan, J., Wang, F., Xu, X., Wang, C., ... & Xu, G. (2022). The miR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGF-β signal pathway. Frontiers in endocrinology, 13.

      182.Wu, S., Cui, Y., Zhao, H., Xiao, X., Gong, L., Xu, H., ... & Li, X. (2022). Trophoblast Exosomal UCA1 Induces Endothelial Injury through the PFN1-RhoA/ROCK Pathway in Preeclampsia: A Human-Specific Adaptive Pathogenic Mechanism. Oxidative medicine and cellular longevity, 2022.

      183.Bai, G., Jiang, X., Qin, J., Zou, Y., Zhang, W., Teng, T., ... & Sun, H. (2022). Perinatal exposure to glyphosate-based herbicides impairs progeny health and placental angiogenesis by disturbing mitochondrial function. Environment International, 107579.

      184.Zhao, X., Xue, X., Wang, J., Dai, S.,Peng, C., & Li, Y. (2022). Quercetin alleviates ethanol-induced hepatic steatosis in L02 cells by activating TFEB translocation to compensate for inadequate autophagy. Phytotherapy Research, 1–15. https://doi.org/10.1002/ptr.7593

      185.Zhou, D., Liao, Z., Chen, X., Fan, Y., & Zuo, H. (2022). LncRNA MHENCR Predicts Poor Outcomes in Patients with Colorectal Carcinoma and Modulates Tumorigenesis by Impairing Mir-532-3p. The Tohoku Journal of Experimental Medicine.

      186.Deng, Y., Xu, X., Meng, F., Lou, J., Liao, Y., Li, Q., ... & Sun, Y. (2022). PRP8-Induced CircMaml2 Facilitates the Healing of the Intestinal Mucosa via Recruiting PTBP1 and Regulating Sec62. Cells, 11(21), 3460.

      187.Gohara, S., Shinohara, K., Yoshida, R., Kariya, R., Tazawa, H., Hashimoto, M., ... & Nakayama, H. (2022). An oncolytic virus as a promising candidate for the treatment of radioresistant oral squamous cell carcinoma. Molecular Therapy-Oncolytics, 27, 141-156.

      188.Ding, J., Wang, S., Liu, Q., Ye, Z., Cui, Z., Zhang, A., ... & Li, X. Schlafen-5 Inhibits LINE-1 Retrotransposition.

      189.Ng, A. S., Zhang, S., Mak, V. C., Zhou, Y., Yuen, Y., Sharma, R., ... & Cheung, L. W. (2022). AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance. Cell Reports, 41(11), 111821.

      190.Ye, Y., Lv, C., Sun, J., Lin, Z., Liu, Y., Huang, Y., ... & Wang, S. (2022). XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma. Oxidative Medicine and Cellular Longevity, 2022.

      191.Li, H., Cheng, S., Huo, J., Dong, K., Ding, Y., Man, C., ... & Jiang, Y. (2023). Lactobacillus plantarum J26 Alleviating Alcohol-Induced Liver Inflammation by Maintaining the Intestinal Barrier and Regulating MAPK Signaling Pathways. Nutrients, 15(1), 190.

      192.Takeshita, H., Yoshida, R., Inoue, J., Ishikawa, K., Shinohara, K., Hirayama, M., ... & Nakayama, H. (2023). FOXM1-mediated regulation of reactive oxygen species and radioresistance in oral squamous cell carcinoma cells. Laboratory Investigation, 100060.

      193.Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., ... & Wang, Z. (2023). Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis. Cellular & Molecular Biology Letters, 28(1), 1-23.

      194.Edwards-Hicks, J., Apostolova, P., Buescher, J. M., Maib, H., Stanczak, M. A., Corrado, M., ... & Pearce, E. L. (2023). Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function. Nature Immunology, 1-15.

      195.Wang, L., Li, S., Cai, K., Xiao, Y., & Ye, L. (2023). TLR7 agonists modulate the activation of human conjunctival epithelial cells induced by IL-1β via the ERK1/2 signaling pathway.

      196.Toll-like Receptor 2 Mediates VEGF Overexpression and Mesothelial Hyperpermeability in Tuberculous Pleural Effusion. International Journal of Molecular Sciences, 24(3), 2846.

      197.Chen, G., & Xie, M. (Eds.). (2023). The nutritional evidence and research on tea (Vol. 16648714). Frontiers Media SA.

      198.Liu, W., Cheng, L., Du, Y., Liu, X., Ma, J., & Yan, L. (2023). 6-(7-Nitro-2, 1, 3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4. Reproductive Sciences, 1-17.

      199.Zhu, D. D., Huang, Y. L., Guo, S. Y., Li, N., Yang, X. W., Sui, A. R., ... & Li, S. (2023). AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav 1.6‐Mediated Astrocyte Autophagy. Advanced Science, 2205862.

      200.Shirono, Y., Bilim, V., Anraku, T., Kuroki, H., Kazama, A., Murata, M., ... & Tomita, Y. (2023). Targeting pro-survival autophagy enhanced GSK-3β inhibition-induced apoptosis and retarded proliferation in bladder cancer cells.

      201.Chen, S. N., Li, B., Gan, Z., Wang, K. L., Li, L., Pang, A. N., ... & Nie, P. (2023). Transcriptional Regulation and Signaling of Type IV IFN with Identification of the ISG Repertoire in an Amphibian Model, Xenopus laevis. The Journal of Immunology, ji2300085.

      202.Lai, C. H., Lai, Y. R., Chang, Y. F., Huang, Y. P., Chou, C. H., Ho, M. W., & Chiu, C. H. (2023). The receptor for advanced glycation end products is involved in Campylobacter jejuni cytolethal distending toxin intracellular trafficking.

      203.Pierce, C. A., Loh, L. N., Steach, H. R., Cheshenko, N., Preston-Hurlburt, P., Zhang, F., ... & Herold, B. C. (2023). HSV-2 triggers upregulation of MALAT1 in CD4+ T cells and promotes HIV latency reversal. The Journal of Clinical Investigation.

      204.Huang, Z., Ding, Z., Xu, Y., Xi, C., He, L., Luo, H., ... & Huang, C. (2023). Downregulation of nuclear STAT2 protein in the spinal dorsal horn is involved in neuropathic pain following chronic constriction injury of the rat sciatic nerve. Frontiers in Pharmacology, 14.

      205.Li, J., Wang, K., Yang, C., Zhu, K., Jiang, C., Wang, M., ... & Jiang, X. (2023). Tumor‐Associated Macrophage‐Derived Exosomal LINC01232 Induces the Immune Escape in Glioma by Decreasing Surface MHC‐I Expression. Advanced Science, 2207067.

      206.Zhengyu, F. A. N. G., Qiongxiang, G. E., Zhi, C. H. E. N., Haixin, Q. I., & ZHENG, B. (2023). NME4 promotes cell malignant process by targeting SMAD2 in colorectal cancer.

      207.Ming, F., Li, B., Yi, S., & Pi, G. (2023). Circ_0087378 intensifies the malignant behavior of non-small cell lung cancer cells in vitro by facilitating DDR1 via sponging miR-199a-5p. Translational Lung Cancer Research, 12(4), 770.

      208.Xu, T., Wei, D., Yang, Z., Xie, S., Yan, Z., Chen, C., ... & Wang, J. (2023). ApoM suppresses kidney renal clear cell carcinoma growth and metastasis via the Hippo-YAP signaling pathway. Archives of Biochemistry and Biophysics, 109642.

      209.Wang, S., You, X., Liu, X., Zhang, F., Zhou, H., Shang, X., & Cai, L. (2023). SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma. iScience, 106994.

      210.Yan, J., Li, Y., Ding, L., Hou, R., Xing, C., Jiang, C., ... & Zhuang, C. (2023). Fragment-Based Discovery of Azocyclic Alkyl Naphthalenesulfonamides as Keap1-Nrf2 Inhibitors for Acute Lung Injury Treatment. Journal of Medicinal Chemistry.

      211.Zhu, Y., Lei, L., Wang, X., Jiang, Q., Loor, J. J., Kong, F., ... & Li, X. (2023). Low abundance of insulin-induced gene 1 contributes to SREBP-1c processing and hepatic steatosis in dairy cows with severe fatty liver. Journal of Dairy Science.

      212.Sun, Y., Xu, L., Zheng, D., Wang, J., Liu, G., Mo, Z., ... & Zhuang, C. (2023). A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease. Redox Biology, 102793.

      213.Li, C. Q., Wang, H. W., Zheng, M. M., & Chen, Q. W. (2023). Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviates atherosclerosis through the modulation of M1 polarization. Journal of Translational Medicine, 21(1), 1-17.

      214.Zeng, Y., Ma, G., Cai, F., Wang, P., Liang, H., Zhang, R., ... & Liu, Y. (2023). SMYD3 drives the proliferation in gastric cancer cells via reducing EMP1 expression in an H4K20me3-dependent manner. Cell Death & Disease, 14(6), 386.

      215.Sun, X., Hu, X., Zhang, Q., Zhao, L., Sun, X., Yang, L., & Jin, M. (2023). Sodium taurocholate hydrate inhibits influenza virus replication and suppresses influenza a Virus-triggered inflammation in vitro and in vivo. International Immunopharmacology, 122, 110544.

      216.Fang, M., Wu, H. K., Pei, Y., Zhang, Y., Gao, X., He, Y., ... & Xiao, R. P. (2023). E3 ligase MG53 suppresses tumor growth by degrading cyclin D1. Signal Transduction and Targeted Therapy, 8(1), 263.

      217.Hao, Y., Li, Z., Zhang, A., Sun, L., Wang, G., Wang, H., & Jia, Z. (2023). The role of PKN1 in glioma pathogenesis and the antiglioma effect of raloxifene targeting PKN1. Journal of Cellular and Molecular Medicine.

      218.Zhou, L., Zhu, L., Wu, X., Hu, S., Zhang, S., Ning, M., ... & Chen, M. (2023). Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease. BMC medicine, 21(1), 1-19.

      219.Sha, L., Li, J., Shen, H., Wang, Q., Meng, P., Zhang, X., ... & Xu, Q. (2023). LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis. Cell Reports, 42(8).

      220.Guan, W., Yuan, J., Li, X., Gao, X., Wang, F., Liu, H., ... & Xu, G. (2023). Cyclin dependent kinase 14 as a paclitaxel-resistant marker regulated by the TGF-β signaling pathway in human ovarian cancer. Journal of Cancer, 14(13), 2538.

      221.Wu, J., Hu, Y., Song, J., Xu, J., Zhang, Q., Chai, Y., ... & Xu, X. (2023). Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation. Cell Death & Disease, 14(9), 592.

      222.Duan, C., Liu, R., Kuang, L., Zhang, Z., Hou, D., Zheng, D., ... & Li, T. (2023). Activated Drp1 Initiates the Formation of Endoplasmic Reticulum‐Mitochondrial Contacts via Shrm4‐Mediated Actin Bundling. Advanced Science, 2304885.

      223.Wang, X., Xu, J., Li, Q., Zhang, Y., Lin, Z., Zhai, X., ... & Zheng, Y. (2023). RNA-binding protein hnRNPU regulates multiple myeloma resistance to selinexor. Cancer Letters, 216486.

      224.Cui, S., Wang, Y., Chen, S., Fang, L., Jiang, Y., Pang, Z., ... & Jia, H. (2023). African swine fever virus E120R inhibited cGAS‐STING‐mediated IFN‐β and NF‐κB pathways. Animal Research and One Health.LY6K

      225.Zhu, L., Xie, Z., Yang, G., Zhou, G., Li, L., & Zhang, S. (2023). Stanniocalcin-1 Promotes PARP1-Dependent Cell Death via JNK Activation in Colitis. Advanced Science, 2304123.

      226.Wang, Y., Zhao, M., Cui, J., Lian, H., Hao, Z., Lou, L., ... & Zhang, X. (2024). Ochratoxin A-enhanced glycolysis induces inflammatory responses in human gastric epithelium cells through mTOR/HIF-1α signaling pathway. Ecotoxicology and Environmental Safety, 270, 115868.

      227.Fu, P., Zhu, R., Gao, W., & Gong, L. (2023). Effects of resistance training on alleviating hypoxia‐induced muscle atrophy: Focus on acetylation of FoxO1. Journal of Cellular and Molecular Medicine.

      228.Macejova, D., Kollar, J., Bobal, P., Otevrel, J., Schuster, D., & Brtko, J. (2024). Triphenyltin isoselenocyanate: a novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer. Molecular and Cellular Biochemistry, 1-16.

      229.Li, L. B., Yang, L. X., Liu, L., Liu, F. R., Li, A. H., Zhu, Y. L., ... & Zhao, X. G. (2024). Targeted inhibition of the HNF1A/SHH axis by triptolide overcomes paclitaxel resistance in non-small cell lung cancer. Acta Pharmacologica Sinica, 1-17.

      230.Liang, L. J., Yang, F. Y., Wang, D., Zhang, Y. F., Yu, H., Wang, Z., ... & Zhou, G. B. (2024). CIP2A induces PKM2 tetramer formation and oxidative phosphorylation in non-small cell lung cancer. Cell Discovery, 10(1), 1-22.

      231.Nishiguch, Y., Fujiwara-Tani, R., Nukaga, S., Nishida, R., Ikemoto, A., Sasaki, R., ... & Kuniyasu, H. (2024). Pterostilbene Induces Apoptosis from Endoplasmic Reticulum Stress Synergistically with Anticancer Drugs That Deposit Iron in Mitochondria. International Journal of Molecular Sciences, 25(5), 2611.

      232.Hou, D., Liu, R., Hao, S., Dou, Y., Chen, G., Liu, L., ... & Duan, C. (2024). Notoginsenoside R1 improves intestinal microvascular functioning in sepsis by targeting Drp1-mediated mitochondrial quality imbalance. Pharmaceutical Biology, 62(1), 250-260.

      233.Yang, W., Wei, Y., Wang, T., Xu, Y., Jin, X., Qian, H., ... & He, S. (2024). Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma. International Journal of Molecular Medicine, 53(4), 1-15.

      234.Li, Z., Mao, K., Liu, L., Xu, S., Zeng, M., Fu, Y., ... & Cheng, Y. (2024). Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function. Cell Reports, 43(3).

      235.Wang, Z., Han, B., Qi, J., Cao, X., Gu, H., & Sun, J. (2024). Chuanzhitongluo capsule improves cognitive impairment in mice with chronic cerebral hypoperfusion via the cholinergic anti-inflammatory pathway. Experimental Gerontology, 189, 112407.

      236.Hou, D., Liao, H., Hao, S., Liu, R., Huang, H., & Duan, C. (2024). Curcumin simultaneously improves mitochondrial dynamics and myocardial cell bioenergy after sepsis via the SIRT1-DRP1/PGC-1α pathway. Heliyon.

      237.Fujiwara-Tani, R., Sasaki, T., Bhawal, U. K., Mori, S., Ogata, R., Sasaki, R., ... & Kuniyasu, H. (2024). Nuclear MAST4 Suppresses FOXO3 through Interaction with AKT3 and Induces Chemoresistance in Pancreatic Ductal Carcinoma. International Journal of Molecular Sciences, 25(7), 4056.

      238.Li, X., Guan, W., Liu, H., Yuan, J., Wang, F., Guan, B., ... & Zhang, L. (2024). Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer. Apoptosis, 1-18.

      239.Du, Y., Wu, M., Song, S., Bian, Y., & Shi, Y. (2024). TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease. Renal Failure, 46(1), 2338933.




    close
    close