作为应用离心管柱滤器提取蛋白及亚细胞结构的先驱

英文特生物技术(北京)有限公司成功研发出五十多个全新的生命科学研究领域蛋白提取产品,其中具有多个特色产品,为蛋白提取分 离带来了新方案, 从原有的溶液法转换为柱式提取法。我公司产品 均具有快捷、易用、产量高及重复性好的特性。在短短几年中,产品 以其稳定的品质获得了世界各国越来越多的科研,药物开发及临床诊 断机构的青睐。



    订购信息:SM-005 / 5266.00 元(50Tests)   SM-005 / 535.00元 (4Tests)

    Minute ™质膜蛋白和细胞组分分离试剂盒 SM-005

    Minute™ Plasma Membrane Protein Isolation and Cell Fractionation Kit

    描述:

    Minute 膜蛋白提取试剂盒通过离心管柱技术配合特定裂解液可以快速从动物细胞或组织中分离天然的膜蛋白。其原理是细胞/组织通过Buffer A致敏,然后细胞以Z字形路径通过离心管柱。在这个过程中细胞膜会破裂,分离出完整的细胞核,因此最终获得的膜蛋白中不含有核膜和核蛋白污染。通过差速离心和密度离心可以把细胞蛋白分为:总膜,细胞核,细胞质,细胞器及质膜,而无需超高速离心。整个操作过程不超过45分钟即可完成。
    应用:

    SDS-PAGE、immunoblottings、ELISA、IP、膜蛋白结构分析、MS、2-D、酶活性检测等其他应用。

    特点:

    1、简单,快速,性价比高;

    2、天然细胞组份分离(细胞质, 细胞器和质膜);

    3、真正未变性的膜蛋白–无表面活性剂及EDTA;

    4、100%保留蛋白活性及蛋白间相互作用;

    5、小样品量。

    储存条件:

    储存于-20℃

    参考文献:SM-005文献列表
    • 1. Kalabus JL, et al. (2013). Viral Attachment Induces Rapid Recruitment of an Innate Immune Sensor (TRIM5α) to the Plasma Membrane. J Innate Immun 5:414-424.
      2. Wen D. et al. (2013). Regulation of BK- expression in the distal nephron by aldosterone and urine pH. Am J Physiol Renal Physiol. 305: F463-F476.
      3. Yang J. et al (2014). PLCy1-PKCy signaling-mediated Hsp90a plasma membrane translocation facilitates tumor metastasis. Traffic; 15(8): 861-78.
      4. Marry E.W. et al (2014). Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles. Thromb Haemost; 111:647-655.
      5. Kutluay, S., et al. (2014). Global Changes in the RNA Binding Specificity of HIV-1 Gag Regulate Virion Genesis, Cell (2014), http://dx.doi.org/10.1016/j.cell.2014.09.057.
      6. Leung W-H. et al.(2015). PRL-3 Mediates the protein Maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60.The Journal of Immunology.doi:10.4049/jimmunol.1400817.
      7. Henry E., et al. (2015). Beyond Glysolysis: GAPDHs are multifunctional enzymes involved in regulation of ROS, autophage, and plant immune responses. PLoS Genet 11(4): e1005199. doi:10.1371/journal. pgen.1005199.
      8. Wen D., et al. (2015). Increased epithelial sodium channel activity contributes to hypertension caused by Na+-Hco- cotransporter electrogenic 2 defficiency. Hypertension. 2015;66:00-00. DOI: 10.1161/HYPERTENSIONAHA.115.05394.
      9. Yamaguchi T., et al. (2015). Expression of BAF57 in ovarian cancer cells and drug sensitivity. Cancer Sci 106 (2015) 359-366. doi: 10.1111/cas.12612.
      10. Wen D. et al. (2015). Deficient acid handling with distal RTA in the NBCe2 knockout mouse. Am J Physiol Renal Physiol (June 24, 2015). doi:10.1152/ajprenal.00163.2015.
      11. Kashiwagi Y, Nagoshi T, Yoshino T, Tanaka TD, Ito K, Harada T, et al. (2015) Expression of SGLT1 in Human Hearts and Impairment of Cardiac Glucose Uptake by Phlorizin during Ischemia- Reperfusion Injury in Mice. PLoS ONE 10(6):e0130605. doi:10.1371/journal.pone.0130605.
      12. Georgiou D. K., et al. (2015). Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism doi: 10.1074/jbc.M115.643544 jbc.M115.643544.

      13. Devarakonda C. V. et al.(2015). Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors. BMC Cancer 2015, 15:614 doi:10.1186/s12885-015-1608-z
      14. Lin Z-J, D.,et al(2015) PBL13 is a serine/threonine protein kinase that negatively regulates Arabidopsis immune responses. Plant Physiology. doi: http://dx.doi.org/10.1104/pp.15.01391
      15. Mickle, A. D., Shepherd, A. J., Loo, L., & Mohapatra, D. P. (2015). Induction of Thermal and Mechanical Hypersensitivity by Parathyroid Hormone-related Peptide (PTHrP) Through Upregulation of TRPV1 Function and Trafficking. Pain, 156(9), 1620.
      16. Izumi D., et al. (2016). CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin b1 clustering and invasiveness in gastric cancer. Int. J. Cancer: 138, 1207–1219.
      17. Sebla B. Kutluay and Paul D. Bieniasz. (2016) Analysis of HIV-1 Gag-RNA Interactions in Cells and Virions by CLIP-seq. Methods in Mol. Biol. 1354, pp 119-131.
      18. Mukai H., et al. (2016) PKN3 is the major regulator of angiogenesis and tumor metastasis in mice. Scientific Reports | 6:18979 | DOI: 10.1038/srep18979.
      19. Tao JQ et al. (2016). Onset of Inflammation with Ischemia: Implications for Donor Lung Preservation and Transplant Survival. American Journal of Transplantation. doi: 10.1111/ajt.13794.
      20. Vazquez-Medina J.P. et al. (2016). The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation vialysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages. The FASEB Journal. doi: 10.1096/fj.201500146R.
      21. Lin W. et al.,( 2016). Syndecan-4 negatively regulates antiviral signaling by mediating RIG-I deubiquitination via CYLD. Nature communications, DOI: 10.1038/ncomms11848. http://www.nature.com/naturecommunications.
      22. Hernández-Saavedra, Daniel, et al.(2016) "RTP801 Amplifies Nox-4-dependent Oxidative Stress Induced by Cigarette Smoke." American Journal of Respiratory Cell and Molecular Biology.
      23. LEE, S. J., PARK, B. N., ROH, J. H., AN, Y. S., HUR, H., & YOON, J. K. (2016). B Enhancing the Therapeutic Efficacy of 2-Deoxyglucose in Breast Cancer Cells Using Cell-cycle Synchronization. Anticancer Research, 36(11), 5975-5980.
      24. Choi, K. M., Kim, W., Hong, J. T., & Yoo, H. S. (2017). Dodeca-2(E),4(E)-dienoic acid isobutylamide enhances glucose uptake in 3T3-L1 cells via activation of Akt signaling. Mol Cell Biochem. DOI 10.1007/s11010-016-2876-x
      25. Hisamatsu, Y., Suzuki, N., Masum, A. A., Shibuya, A., Abe, R., Sato, A. & Aoki, S. (2017).Cationic Amphiphilic Tris-Cyclometalated Iridium(III) Complexes Induce Cancer Cell Death via Interaction with Ca2+-Calmodulin Complex. Bioconjugate Chem. DOI: 10.1021/acs.bioconjchem.6b00627
      26. Sun, X., Tao, L., Yi, L., Ouyang, Y., Xu, N., Li, D., & Zhang, Z. (2017).N-glycans released from glycoproteins using a commercial kit and comprehensively analyzed with a hypothetical database. Journal of Pharmaceutical Analysis. DOI: http://dx.doi.org/10.1016/j.jpha.2017.01.004
      27. Luo, Y., Duan, H., Qian, Y., Feng, L., Wu, Z., Wang, F., ... & Yan, X. (2017). Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Research (2017) :1-21. doi:10.1038/cr.2017.8
      28. Zheng, J., Zhao, Y., Lun, Q., Song, Y., Shi, S., Gu, X., ... & Tu, P. (2017). Corydalis edulis Maxim. Promotes Insulin Secretion via the Activation of Protein Kinase Cs (PKCs) in Mice and Pancreatic β Cells. Scientific RepoRts | 7:40454 | DOI: 10.1038/srep40454

      29. Hoshi, Y., Uchida, Y., Tachikawa, M., Ohtsuki, S., & Terasaki, T. (2017). Actin filament‐associated protein 1 (AFAP‐1) is a key mediator in inflammatory signaling‐induced rapid attenuation of intrinsic P‐gp function in human brain capillary endothelial cells. Journal of Neurochemistry.
      30. Xu N, et al(2017). Hypokalemia and Pendrin Induction by Aldosterone. Hypertension. doi.org/10.1161/HYPERTENSIONAHA.116.08519
      31. Hayashiuchi, M., Kitayama, T., Morita, K. et al. J Anesth (2017) General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice. Journal of Anesthesia, 1-8. doi:10.1007/s00540-017-2350-2.
      32. Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S.(2017). The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. eLife 2017;6:e26362. DOI: 10.7554/eLife.26362
      33. Ueda, K., Nishimoto, M., Hirohama, D., Ayuzawa, N., Kawarazaki, W., Watanabe, A., ... & Fujita, T. (2017).Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension. Hypertension. 2017;70:111-118. DOI: 10.1161/HYPERTENSIONAHA.116.08966.
      34. Asano, S., Taniguchi, Y., Yamawaki, Y., Gao, J., Harada, K., Takeuchi, H., ... & Kanematsu, T. (2017).Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling.Sci Rep. 2017 Jul 14;7(1):5408. doi: 10.1038/s41598-017-05908-7.
      35. Bugge, M., Bergstrom, B., Eide, O. K., Solli, H., Kjønstad, I. F., Stenvik, J., ... & Nilsen, N. J. (2017). Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness. J Biol Chem. 2017 Jul 17. pii: jbc.M117.784090. doi: 10.1074/jbc.M117.784090. [Epub ahead of print]
      36. Murgueitio, M. S., Ebner, S., Hörtnagl, P., Rakers, C., Bruckner, R., Henneke, P., ... & Santos-Sierra, S. (2017). Enhanced immunostimulatory activity of in silico discovered agonists of Toll-like receptor 2 (TLR2).Biochim Biophys Acta. 2017 Jul 19. pii: S0304-4165(17)30222-2. doi: 10.1016/j.bbagen.2017.07.011. [Epub ahead of print]
      37. Gu, S., Sachleben, J. R., Boughter, C. T., Nawrocka, W. I., Borowska, M. T., Tarrasch, J. T., ... & Adams, E. J. (2017).,Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation . PNAS 2017 ; August 14, 2017, doi: 10.1073/pnas.1707547114 [PNAS ahead of print]
      38. Ferioli, S., Zierler, S., Zaißerer, J., Schredelseker, J., Gudermann, T., & Chubanov, V. (2017). TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg· ATP. Scientific Reports, 7.
      39. Sugimoto, R., Watanabe, H., Ikegami, K., Enoki, Y., Imafuku, T., Sakaguchi, Y., ... & Tanaka, M. (2017). Down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism. Kidney international, 91(3), 658-670.
      40. Lee, A., Choi, K. M., Jung, W. B., Jeong, H., Kim, G. Y., Lee, J. H., ... & Yoo, H. S. (2017).Enhancement of Glucose Uptake by Meso-Dihydroguaiaretic Acid through GLUT4 Up-Regulation in 3T3-L1 Adipocytes. Molecules 2017, 22, 1423; doi:10.3390/molecules22091423
      41. Thornton, P., Sevalle, J., Deery, M. J., Fraser, G., Zhou, Y., Ståhl, S., ... & Nicol, L. S. (2017).TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant. EMBO Molecular Medicine.30 AUG 2017.DOI: 10.15252/emmm.201707673

      42. Toyoki, D., Shibata, S., Kuribayashi-Okuma, E., Xu, N., Ishizawa, K., Hosoyamada, M., & Uchida, S. (2017).Insulin stimulates uric acid reabsorption via regulating urate transporter 1 and ATP-binding cassette subfamily G member 2. Am J Physiol Renal Physiol 313: F826–F834, 2017.

      43. Thorwald, M., Rodriguez, R., Lee, A., Martinez, B., Peti-Peterdi, J., Nakano, D., ... & Ortiz, R. M. (2017).Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats. Redox Biology 14 (2018) 371–378
      44. Jing Liu, Wensu Liu, Jun Zhang, Fuchou Tang,Xiaoqun Wang et al.(2017).The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding. Cell Stem Cell (2017), doi.org/10.1016/j.stem.2017.08.013
      45. Yokoi, K., Hisamatsu, Y., Naito, K. and Aoki, S. (2017), Design, Synthesis, and Anticancer Activities of Cyclometalated Tris(2-phenylpyridine)iridium(III) Complexes with Cationic Peptides at the 4′-Position of the 2-Phenylpyridine Ligand. Eur. J. Inorg. Chem.. doi: 10.1002/ejic.20170084
      46. The article is unauthorized
      47. Hongli Liu, Xiaofei Xu, Ting Han, Lei Yan, Lei Cheng, Yingying Qin(2017). A novel homozygous mutation in the FSHR gene is causative for primary ovarian insufficiency.Fertility and Sterility .Available online 20 November 2017. doi.org/10.1016/j.fertnstert.2017.09.010.
      48. Kevin T.Chapman etal(2017).US Patent Application Publication Chapman etal. Pub No:2017/0276679A1 Pub.Date Sep.28.2017
      49. Bok-Nam Park, PhD,etal(2017).Radiolabeled Anti-Adenosine Triphosphate Synthase Monoclonal Antibody as a Theragnostic Agent Targeting Angiogenesis.Molecular Imaging. doi.org/10.1177/1536012117737399
      50. Ye Tian Dai Heng Kaili Xu Wenbo Liu Xuechun Weng Xusong Hu Cheng Zhang(2017).cGMP/PKG-I pathway-mediated GLUT1/4 regulation by NO (nitric oxide) in female rat granulosa cells. Endocrinology, en.2017-00863, doi.org/10.1210/en.2017-00863
      51. Naoya KAMEYAMA, Tokyo (JP);Munetoshi ANDO, Tokyo (JP); ShinyaOGAWA, Tokyo (JP); KazukiOKADA, Tokyo (JP)(2018).ANTIBODY WHICH SPECIFICALLY BINDS TO HUMAN CRTH2 .Patent Application Publication May 4, 2017. Sheet 9 of 17 US 2017/O121415 A1
      52. KEVIN P. CLAFFEY, BURLINGTON, CT (US); CHARAN DEVARAKONDA, WILLIMANI*IC, CT (US); DANIEL KITA, CHESHIRE, CT (US)(2018) .ANTIBODY AND ANTIGEN-BINDING FRAGMENT COMPOSITIONS TARGETING CELL SURFACE ANIIGENS IN TUMORS AND METHODS OF USE THEREOF .Patent Application Publication A. Jan. 4, 2018 Sheet 4 Of 11 - Miq 'osoft US 2018/0002412 Al
      53. Li C, Du S, Tian M, Wang Y, Bai J, Tan P, Liu W, Yin R, Wang M, Jiang Y, Li Y, Zhu N, Zhu Y, Li T, Wu S, Jin N and He F (2018) .The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection. Front. Immunol. 9:228. doi: 10.3389/fimmu.2018.00228
      54. Lin Long,Xiao-Xiao Pang,Fei Lei ,Jia-Sheng Zhang,Wei Wang ,Lian‑Di Liao, Xiu‑E Xu,Jian‑Zhong He, Jian‑Yi Wu, Zhi‑Yong Wu, Li‑Dong Wang,De‑Chen Lin,En‑Min Li, Li‑Yan Xu(2018). SLC52A3 expression is activated by NF-κB p65/Rel-B and serves as a prognostic biomarker in esophageal cancer.Cellular and Molecular Life Sciences doi.org/10.1007/s00018-018-2757-4
      55. Y. Yu,Y. Zhao,F. Teng,J. Li,Y. Guan,J. Xu,X. Lv,F. Guan,Ming Zhang, L. Chen(2018). Berberine Improves Cognitive Deficiency and Muscular Dysfunction Via Activation of the AMPK/SIRT1/PGC-1A Pathway in Skeletal Muscle from Naturally Aging Rats. J Nutr Health Aging (2018).doi.org/10.1007/s12603-018-1015-7

      56. Xi Song, _ Qiyang Shen, Liting Fan, Qiuxiao Yu, Xiao Jia, Yu Sun, Wenpei Bai, Jihong Kang(2018).Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of polycystic ovary syndrome.Oncotarget. 2018; 9:11905-11921. doi.org/10.18632/oncotarget.24190
      57. Yin et al(2018).Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone.Journal of Neuroinflammation (2018) 15:97, doi.org/10.1186/s12974-018-1127-3.
      58. XiaoLong Zhang , HuanHuan Ding,Ting Xu, Meng Liu, Chao Ma(2018).Palmitoylation of δ-catenin promotes kinesin-mediated membrane trafficking of Nav1.6 in sensory neurons to promote neuropathic pain. Signal. 27 Mar 2018:Vol. 11, Issue 523, eaar4394,DOI: 10.1126/scisignal.aar4394.
      59. Yamauchi, T., Doi, S., Nakashima, A., Doi, T., Sohara, E., Uchida, S., & Masaki, T. (2018). Na+-Cl− cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats. American Journal of Physiology-Renal Physiology.doi.org/10.1152/ajprenal.00504.2016
      60. Kameyama, Naoya, A. N. D. O. Munetoshi, Shinya Ogawa, and Kazuki Okada. "Antibody which specifically binds to human CRTH2." U.S. Patent 9,938,349, issued April 10, 2018.
      61. Kyeong-Mi Choi , Hwan-Soo Yoo(2018). 3,3-Diindolylmethane Enhances Glucose Uptake ThroughActivation of Insulin Signaling in 3T3-L1 Adipocytes.OBESITY BIOLOGY AND INTEGRATED PHYSIOLOGY. doi:10.1002/oby.22145
      62. Qingyang Liu, Yan Zhao, Li Zheng, Xiaotong Zhu, Liwang Cui1, and Yaming Cao(2018).The GPI transamidase complex subunit PbGPI16 of Plasmodium berghei is important for inducing experimental cerebral malaria.Infect. Immun. doi:10.1128/IAI.00929-17.
      63. Wu, Y., Liu, T., Yuan, Y., & Zhang, Z. (2018). Gene expression profile of TLR7 signaling pathway in the liver of rhesus rotavirus-induced murine biliary atresia. Biochemical and biophysical research communications.doi.org/10.1016/j.bbrc.2018.06.018.
      64. Komatsu, W., Kishi, H., Yagasaki, K., & Ohhira, S. (2018). Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species. European Journal of Pharmacology doi.org/10.1016/j.ejphar.2018.06.023.
      65. Y Uchida, T Sumiya, M Tachikawa, T Yamakawa etal(2018).Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis. Molecular Neurobiology. doi.org/10.1007/s12035-018-1207-5
      66. Shibata et al., (2018).ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor.Cell Reports 24, 569–576 July 17, 2018 ª 2018 The Author(s).doi.org/10.1016/j.celrep.2018.06.072
      67. Jinliang Wang , Zilong Wang , Renqiang Liu , Lei Shuai, Xinxin Wang, Jie Luo, Chong Wang, Weiye Chen, Xijun Wang, Jinying Ge, Xijun He, Zhiyuan Wen , Zhigao Bu (2018).Metabotropic glutamate receptor subtype 2 is a cellular receptor for rabies virus.PLoS Pathog. 2018 Jul 20;14(7):e1007189. doi.org/10.1371/journal.ppat.1007189.
      68. Liu Q, Zhao Y, Zheng L, Zhu X, Cui L, Cao Y(2018).The Glycosylphosphatidylinositol Transamidase Complex Subunit PbGPI16 of Plasmodium berghei Is Important for Inducing Experimental Cerebral Malaria.Infect Immun. 2018 Jul 23;86(8). doi: 10.1128/IAI.00929-17.
      69. DY Liu,etal(2018).Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.Exp Neurol. 2018 Jul 10;308:90-99. doi: 10.1016/j.expneurol.2018.07.002.

      70. Timothy Sean Kairupan, etal(2018). Rubiscolin-6 activates opioid receptors to enhance glucose uptake in skeletal muscle. Journal of Food and Drug Analysis . DOI: 10.1016/j.jfda.2018.06.012
      71. He X et al (2018).Downregulation of MicroRNA-4463 Attenuates High-Glucose- and Hypoxia-Induced Endothelial Cell Injury by Targeting PNUTS.Cell Physiol Biochem. doi: 10.1159/000493717.
      72. D Hirohama etal (2018).Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin. JASN January 2018, 29 (1) 57-68; DOI: https://doi.org/10.1681/ASN.2017030243.
      73. Thorwald, Max Andrew(2018).The Regulation of Cardiac Nrf2 During an Acute Glucose Challenge and the Impact on Mitochondrial Function During Insulin Resistance and Type II Diabetes Mellitus. Doctor of Philosophy in Quantitative and Systems Biology of University of California. https://escholarship.org/uc/item/5zt6z1bv.
      74. Xiaoqing Xu, Jia Xu, Jiacheng Wu, Ye Hu, Yanmei Han, Yan Gu, Kai Zhao, Qian Zhang, Xingguang Liu, Juan Liu, Bing Liu, and Xuetao Cao (2018).Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response.cell.doi.org/10.1016/j.cell.2018.09.011.
      75. Md Badrul Alam etal (2018). Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes.Oxidative Medicine and Cellular Longevity.doi.org/10.1155/2018/5796102.
      76. D Hakuno etal (2018).Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Scientific Reports.DOI: 10.1038/s41598-018-35194-w.
      77. DataoWang etal (2018).Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC⁻MS/MS. Int J Mol Sci. 2018 Nov 5;19(11). pii: E3477. doi: 10.3390/ijms19113477.
      78. Kuroda H etal (2018).Cluster of Differentiation 46 is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28).Mol Pharm. 2018 Nov 19. doi: 10.1021/acs.molpharmaceut.8b00985.
      79. Kataoka, Y., Ohshio, Y., Teramoto, K., Igarashi, T., Asai, T., & Hanaoka, J. Hypoxia‑induced galectin‑3 enhances RhoA function to activate the motility of tumor cells in non‑small cell lung cancer. Oncology Reports.DOI: 10.3892/or.2018.6915.
      80. Hoshi, Y., Uchida, Y., Tachikawa, M., Ohtsuki, S., Couraud, P. O., Suzuki, T., & Terasaki, T. (2019). Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood–brain barrier. Journal of Cerebral Blood Flow & Metabolism, DOI: 10.1177/0271678X18822801.
      81. Zhang N et al (2018).Fatty Acid Synthase Promotes the Palmitoylation of Chikungunya Virus nsP1. J Virol. Doi: 10.1128/JVI.01747-18.
      82. H Nakamura et al (2019).Exploration of Proteins Involved in Acquisition of Resistance to Cetuximab. jurnal.unpad.ac.id.doi.org/10.24198/idjp.v1i1.19582.
      83. Polioudaki, H., Chantziou, A., Kalyvianaki, K., Malamos, P., Notas, G., Mavroudis, D., ... & Theodoropoulos, P. A. (2019). Nuclear localization of PD-L1: artifact or reality?. Cellular Oncology.doi.org/10.1007/s13402-018-00419-7.
      84. Ishizawa, K., Wang, Q., Li, J., Yamazaki, O., Tamura, Y., Fujigaki, Y., ... & Shibata, S. (2019). Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling. Proceedings of the National Academy of Sciences, 201817281.
      85. Nemoto, Y., Kumagai, T., Ishizawa, K., Miura, Y., Shiraishi, T., Morimoto, C., ... & Fujigaki, Y. (2019). Phosphate binding by sucroferric oxyhydroxide ameliorates renal injury in the remnant kidney model. Scientific Reports, 9(1), 1732.Doi.org/10.1038/s41598-018-38389-3.

      86. .Li, Y., Yang, T., Yao, Q., Li, S., Fang, E., Li, Y., ... & Li, W. (2019). Metformin prevents colonic barrier dysfunction by inhibiting mast cell activation in maternal separation-induced IBS-like rats. Neurogastroenterology & Motility. DOI: 10.1111/nmo.13556.
      87. Peng, W., Tong, C., Li, L., Huang, C., Ran, Y., Chen, X., ... & Luo, X. (2019). Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia. The FASEB Journal, fj-201802058RR.Doi: 10.1096/fj.201802058RR.
      88. Zhong, W., Xu, M., Li, C., Zhu, B., Cao, X., Li, D., ... & Pan, G. (2019). ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells. Cell Reports, 26(8), 2166-2177.Doi.org/10.1016/j.celrep.2019.01.082.
      89. Zhang, S. H., Liu, D. X., Wang, L., Li, Y. H., Wang, Y. H., Zhang, H., ... & Li, B. (2019). A CASPR1–ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells. Journal of Biological Chemistry, jbc-RA118. Doi/10.1074/jbc.RA118.006263.
      90. Nagamine, A., Araki, T., Nagano, D., Miyazaki, M., & Yamamoto, K. L‑Lactate dehydrogenase B may be a predictive marker for sensitivity to anti‑EGFR monoclonal antibodies in colorectal cancer cell lines. Oncology Letters.DOI: 10.3892/ol.2019.10075
      91. Essandoh, K., Deng, S., Wang, X., Jiang, M., Mu, X., Peng, J., ... & Fan, G. C. (2019). Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R. The FASEB Journal, fj-201802338RR.doi: 10.1096/fj.201802338RR.
      92. Ishizawa, K., Wang, Q., Li, J., Xu, N., Nemoto, Y., Morimoto, C., ... & Fujita, T. (2019). Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice. Journal of the American Society of Nephrology, ASN-2018070703.Doi.org/10.1681/ASN.2018070703.
      93. Van Krieken, R., Mehta, N., Wang, T., Zheng, M., Li, R., Gao, B., ... & Austin, R. C. (2019). Cell surface expression of 78 kDa glucose regulated protein (GRP78) mediates diabetic nephropathy. Journal of Biological Chemistry, jbc-RA118.Doi/10.1074/jbc.RA118.006939.
      94. Li, C., Wang, X., Cheng, F., Du, X., Yan, J., Zhai, C., ... & Wang, Q. (2019). Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system. European Journal of Pharmacology.doi.org/10.1016/j.ejphar.2019.04.021.
      95. Ni, H. M., Chao, X., Kaseff, J., Deng, F., Wang, S., Shi, Y. H., ... & Jaeschke, H. (2019). Receptor-Interacting Serine/Threonine Kinase 3 (RIP3)–Mixed Lineage Kinase Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers. The American Journal of Pathology.doi.org/10.1016/j.ajpath.2019.03.010
      96. Sheng, J., Shen, L., Sun, L., Zhang, X., Cui, R., & Wang, L. (2019). Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial‐lysosomal crosstalk. Cell Proliferation, e12609.
      97. Ghosh, M., Lo, R., Ivic, I., Aguilera, B., Qendro, V., Devarakonda, C., & Shapiro, L. H. (2019). CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration. Signal., 12(579), eaav5938.DOI: 10.1126/scisignal.aav5938

      98. .Liu, W., Wang, X., Wang, S., Ba, X., Xu, T., Wang, X., & Zeng, X. RhoGDI2 positively regulates the Rho GTPases activation in response to the β2 outside‐in signaling in T cells adhesion and migration on ICAM‐1. Journal of Leukocyte Biology.DOI: 10.1002/JLB.2A0718-272RR
      99. Chang, W., Callan, K. T., & Dragoo, J. L. (2019). The Behavior of Tendon Progenitor Cells from Tendinopathic Tendons: Implications for Treatment. Tissue Engineering, (ja).DOI: 10.1089/ten.TEA.2019.0042
      100. Wang, D., Zheng, J., Hu, Q., Zhao, C., Chen, Q., Shi, P., ... & Pei, J. (2019). Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis. Cell Death & Differentiation, 1.doi.org/10.1038/s41418-019-0366-x
      101. Yoshii, A., Nagoshi, T., Kashiwagi, Y., Kimura, H., Tanaka, Y., Oi, Y., ... & Yoshimura, M. (2019). Cardiac ischemia–reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity. Cardiovascular Diabetology, 18(1), doi.org/10.1186/s12933-019-0889-y
      102. Scheiber, I. F., Alarcon, N. O., & Zhao, N. (2019). Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14. Nutrients, 11(7), 1473.doi:10.3390/nu11071473
      103. Yan Zhang, et al (2019).Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy. Cell research, 1.doi.org/10.1038/s41422-019-0184-1
      104. Xu, B. Y., Tang, X. D., Chen, J., Wu, H. B., Chen, W. S., & Chen, L. (2019). Rifampicin induces clathrin-dependent endocytosis and ubiquitin–proteasome degradation of MRP2 via oxidative stress-activated PKC-ERK/JNK/p38 and PI3K signaling pathways in HepG2 cells. Acta Pharmacologica Sinica, 1.doi.org/10.1038/s41401-019-0266-0
      105. XuYue , Ping Zhou, Sen Cheng, ...,Jingjin Ding, Michael O. Hottiger,Feng Shao.(2019)A Bacterial Effector Reveals the V-ATPase-ATG16L1Axis that Initiates Xenophagy.Cell.doi.org/10.1016/j.cell.2019.06.007
      106. Ishii, S., Kitazawa, H., Mori, T., Kirino, A., Nakamura, S., Osaki, N., ... & Tamai, I. (2019). Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice. Scientific Reports, 9(1), 11014.doi.org/10.1038/s41598-019-47214-4
      107. Ljungars, A., Svensson, C., Carlsson, A., Birgersson, E., Tornberg, U. C., Frendéus, B., ... & Mattsson, M. (2019). Deep mining of complex antibody phage pools generated by cell panning enables discovery of rare antibodies binding new targets and epitopes. Frontiers in Pharmacology, 10. doi: 10.3389/fphar.2019.00847
      108. Park, B. N., Kim, G. H., Ko, S. A., Shin, G. H., Lee, S. J., An, Y. S., & Yoon, J. K. (2019). Zr-89 Immuno-PET Targeting Ectopic ATP Synthase Enables In-Vivo Imaging of Tumor Angiogenesis. International journal of molecular sciences, 20(16), 3928.doi:10.3390/ijms20163928
      109. Zhang, H., Tian, X., Lu, X., Xu, D., Guo, Y., Dong, Z., ... & Yang, M. (2019). TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation. The Journal of Clinical Investigation, 129(9).doi.org/10.1172/JCI122599.
      110. Bai, Y., Ma, L. T., Chen, Y. B., Ren, D., Chen, Y. B., Li, Y. Q., ... & Yi, X. N. (2019). Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats. Molecular Brain, 12(1), 1-20.doi:10.1105/tpc.18.00706
      111. Wu, J., Gao, F., Xu, T., Li, J., Hu, Z., Wang, C., ... & Zhou, B. (2019). CLDN1 induces autophagy to promote proliferation and metastasis of esophageal squamous carcinoma through AMPK/STAT1/ULK1 signaling. Journal of Cellular Physiology.doi.org/10.1002/jcp.29133
      112. Li, W., Zhang, J., Zou, L., Cui, J., Su, F., Jin, J., ... & Zhao, G. Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants. Oncology Reports.doi: 10.3892/or.2019.7333.

      113. Huang, S., Liu, C., Li, N., Wu, Z., Li, T., Han, D., ... & Wang, J. (2019). Membrane proteomic analysis reveals the intestinal development is deteriorated by intrauterine growth restriction in piglets. Functional & Integrative Genomics, 1-15.doi.org/10.1007/s10142-019-00714-y.
      114. Jiang, A. (2019). Identifying Interactions Between Chikungunya Virus And Aedes Aegypti Salivary Gland Proteins.
      115. Fujimoto, B. A., Young, M., Carter, L., Pang, A. P., Corley, M. J., Fogelgren, B., & Polgar, N. (2019). The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. American Journal of Physiology-Endocrinology and Metabolism.
      116. Takahashi, N., Kimura, A. P., Otsuka, K., Ohmura, K., Naito, S., Yoshida, M., & Ieko, M. (2019). Dreh, a long noncoding RNA repressed by metformin, regulates glucose transport in C2C12 skeletal muscle cells. Life Sciences, 116906.
      117. Liu, F., Liu, Q., Yu, C., Zhao, Y., Wu, Y., Min, H., ... & Cao, Y. (2019). An MFS-Domain Protein Pb115 Plays a Critical Role in Gamete Fertilization of the Malaria Parasite Plasmodium berghei.Front Microbiol. 2019; 10: 2193.doi: 10.3389/fmicb.2019.02193.
      118. Börtlein, C., Schumacher, F., Kleuser, B., Dölken, L., & Avota, E. (2019). Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis. Frontiers in Cell and Developmental Biology, 7.
      119. Mücksch, F., Citir, M., Lüchtenborg, C., Glass, B., Traynor-Kaplan, A., Schultz, C., ... & Kräusslich, H. G. (2019). Quantification of phosphoinositides reveals strong enrichment of PIP 2 in HIV-1 compared to producer cell membranes. Scientific Reports, 9(1), 1-13.
      120. Claffey, K. P., Devarakonda, C., & Kita, D. (2019). U.S. Patent Application No. 16/533,937.
      121. Wang, C., Wang, J., Shuai, L., Ma, X., Zhang, H., Liu, R., ... & Bu, Z. (2020). The Serine/Threonine Kinase AP2-Associated Kinase 1 Plays an Important Role in Rabies Virus Entry. Viruses, 12(1), 45.
      122. Li, L., Zhang, L., Hu, Q., Zhao, L., Nan, Y., Hou, G., ... & Tao, H. (2020). MYH9 Key Amino Acid Residues Identified by the Anti-Idiotypic Antibody to Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 5 Involve in the Virus Internalization by Porcine Alveolar Macrophages. Viruses, 12(1), 40.
      123. Fukuyama K, Fukuzawa M,Shiroyama T, Okada M. Pathogenesis and pathophysiology of autosomal dominant sleep-related hypermotor epilepsy with S284L-mutant α4 subunit of nicotinic ACh receptor. BrJ Pharmacol. 2020;177:2143–2162. https://doi.org/10.1111/bph.14974
      124. Y Gong,et al (2020).Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent Manner. Cells.
      125. Wenjie Zhong, Huaxiang Zhao, Wenbin Huang, Mengqi Zhang, Qian Zhang, Yue Zhang, Chong Chen, Zulihumaer Nueraihemaiti, Dilifeire Tuerhong, Huizhe Huang,Gulibaha Maimaitili, Feng Chen, Jiuxiang Lin(2020).Identification of rare PTCH1 nonsense variant causing orofacial cleft in a Chinese family and an up-to-date genotype-phenotype analysis.Genes & Diseases
      126. Xu, M., Zhu, B., Cao, X., Li, S., Li, D., Zhou, H., ... & Yan, D. (2020). OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis. The Journal of Immunology.
      127. Sakai, K., Yamazaki, O., Ishizawa, K., Tamura, Y., Wang, Q., Ueno, M., ... & Shibata, S. (2020). Upregulation of renal Na–K–2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway. Biochemical and Biophysical Research Communications.

      128. .Yuan, J., Zheng, Z., Wang, L., Ran, H., Tang, X., Xie, X., ... & Zhang, J. (2020). The Dynll1-Cox4il Complex Regulates Intracellular Pathogen Clearance via Release of Mitochondrial Reactive Oxygen Species. Infection and Immunity.Fukuyama, K., Okubo, R., Murata, M., Shiroyama, T., & Okada, M. (2020).
      129. Kouji Fukuyama et al (2020).Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine. Cells, 9(2), 414.
      130. Duan, X., Liu, X., Liu, N., Huang, Y., Jin, Z., Zhang, S., ... & Chen, H. (2020). Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation. Cell Death & Disease, 11(2), 1-14
      131. Li, S., Shi, B., Huang, K., & Wang, Y. (2020). Different intracellular signalling sensitivity and cell behaviour of porcine insulin with aging. Peptides, 127, 170278.
      132. Yang, L., Zhou, G., Li, M., Li, Y., Yang, L., Fu, Q., & Tian, Y. High Glucose Downregulates Connexin 43 Expression and Its Gap Junction and Hemichannel Function in Osteocyte-like MLO-Y4 Cells Through Activation of the p38MAPK/ERK Signal Pathway.
      133. Yoon, J. K., Byeon, H. E., Ko, S. A., Park, B. N., An, Y. S., Lee, H. Y., ... & Lee, S. J. (2020). Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon cancer. Scientific Reports, 10(1), 1-7.
      134. Wang, Q., Wang, Y., Ding, J., Wang, C., Zhou, X., Gao, W., ... & Liu, Z. (2020). A bioorthogonal system reveals antitumour immune function of pyroptosis. Nature, 1-7.

      135. Wang, Y., Chen, J., Li, S., Zhang, X., Guo, Z., Hu, J., ... & Yang, G. (2020). Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biology, 101514.

      136. Ma, L., Chen, X., Zhao, B., Shi, Y., & Han, F. (2020). Enhanced apoptosis and decreased AMPA receptors are involved in deficit in fear memory in Rin1 knockout rats. Journal of Affective Disorders.

      137. Yuan, J., Zheng, Z., Wang, L., Ran, H., Tang, X., Xie, X., ... & Zhang, J. (2020). The Dynll1-Cox4i1 Complex Regulates Intracellular Pathogen Clearance via Release of Mitochondrial Reactive Oxygen Species. Infection and Immunity, 88(4).

      138. Fukuyama, K., Fukuzawa, M., Okubo, R., & Okada, M. (2020). Upregulated Connexin 43 Induced by Loss-of-Functional S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Contributes to Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. Pharmaceuticals, 13(4), 58.

      139. Chen, L., Li, X., Wang, H., Hou, P., & He, H. (2020). Annexin A2 gene interacting with viral matrix protein to promote bovine ephemeral fever virus release. Journal of Veterinary Science, 21

      140. Zhang, Y., Zhou, P., Wang, Z., Chen, M., Fu, F., & Su, R. (2020). Hsp90β positively regulates μ-opioid receptor function. Life Sciences, 117676.

      141. Bogucka, K., Pompaiah, M., Marini, F., Binder, H., Harms, G., Kaulich, M., ... & Grimminger, P. (2020). ERK3/MAPK6 controls IL-8 production and chemotaxis. eLife, 9, e52511.

      142.Han, S., Sun, J., Yang, L., & Qi, M. (2020). Role of NDP-and FZD4-Related Novel Mutations Identified in Patients with FEVR in Norrin/β-Catenin Signaling Pathway. BioMed Research International, 2020.

      143.Yang, Z., Ma, J., Yang, X., Gao, G., & Zhou, T. (2020). Elevated pigment epithelium-derived factor induces diabetic erectile dysfunction via interruption of the Akt/Hsp90β/eNOS complex.

      144.Fukuyama, K., Fukuzawa, M., & Okada, M. (2020). Upregulated and Hyperactivated Thalamic Connexin 43 Plays Important Roles in Pathomechanisms of Cognitive Impairment and Seizure of Autosomal Dominant Sleep-Related Hypermotor Epilepsy with S284L-Mutant α4 Subunit of Nicotinic ACh Receptor. Pharmaceuticals, 13(5), 99.

      145.Ding, Y., Zhou, Z., Chen, J., Peng, Y., Wang, H., Qiu, W., ... & Zhang, J. (2020). Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from amino-terminal domain of the GluN1 subunit.

      146.Huang, B., Qian, Y., Xie, S., Ye, X., Chen, H., Chen, Z., ... & Héroux, P. (2020). Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y 12 signaling pathway. Cellular & Molecular Immunology, 1-12.

      147.Liu, Y. T., Liu, F., Cao, L., Xue, L., Gu, W. T., Zheng, Y. Z., ... & Xie, W. Q. (2020). The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment. Acta Neuropathologica, 1-20.

      148.Wang, C., Kawakami-Mori, F., Kang, L., Ayuzawa, N., Ogura, S., Koid, S. S., ... & Chen, X. (2020). Low dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents. Kidney International.

      149.Li, Z. Y., Shi, Y. L., Liang, G. X., Yang, J., Zhuang, S. K., Lin, J. B., ... & Zhang, H. T. (2020). Visualization of GLUT1 Trafficking in Live Cancer Cells by the Use of a Dual-Fluorescence Reporter. ACS Omega.

      150.Wang, C., Li, Y., Yan, S., Wang, H., Shao, X., Xiao, M., ... & Zhang, N. (2020). Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2. Nature Communications, 11(1), 1-15.

      151.Yan, P., Patel, H. J., Sharma, S., Corben, A., Wang, T., Panchal, P., ... & Joshi, S. (2020). Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone. Cell Reports, 31(13), 107840.

      152.Zhang, B., Sun, P., Liu, X., Sun, J., Li, D., Liu, Z., ... & Niu, Y. (2020). Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns. Life Sciences, 118145.

      153.Zhou, Y., Du, B., Kan, M., Chen, S., Tang, B. H., Nie, A. Q., ... & Han, Q. J. (2020). Drug Elimination Alteration in Acute Lymphoblastic Leukemia Mediated by Renal Transporters and Glomerular Filtration. Pharmaceutical Research, 37(8), 1-8.

      154.Matamoros, T., Alejo, A., Rodríguez, J. M., Hernáez, B., Guerra, M., Fraile-Ramos, A., & Andrés, G. (2020). African Swine Fever Virus Protein pE199L Mediates Virus Entry by Enabling Membrane Fusion and Core Penetration. mBio, 11(4).

      155.Essandoh, K., Deng, S., Wang, X., Li, Y., Li, Q., Mu, X., ... & Fan, G. C. (2020). Tsg101 Is Involved in the Sorting and Re-Distribution of Glucose Transporter-4 to the Sarcolemma Membrane of Cardiac Myocytes. Cells, 9(9), 1936.

      156.Chen, Y., Zhao, Z., Li, Y., Li, L., Jiang, Y., Cao, Y., ... & Pang, J. (2020). Characterizations of the Urate Transporter, GLUT9, and Its Potent Inhibitors by Patch-Clamp Technique. SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2472555220949501.

      157.Furuhata, R., Kabe, Y., Kanai, A., Sugiura, Y., Tsugawa, H., Sugiyama, E., ... & Tanaka, H. (2020). Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes. Communications Biology, 3(1), 1-13.

      158.Wang, Y., Wang, Y., Li, F. et al. Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System. Cardiovasc Drugs Ther (2020). https://doi.org/10.1007/s10557-020-07064-z

      159.Koponen A, Pan G, Kivelä AM, et al. ORP2, a cholesterol transporter, regulates angiogenic signaling in endothelial cells. The FASEB Journal. 2020;00:1–24. https://doi.org/10.1096/fj.202000202R

      160.Talwar, D., Messens, J. & Dick, T.P. A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex. Nat Commun 11, 4512 (2020). https://doi.org/10.1038/s41467-020-18324-9

      161.Shiheido-Watanabe, Y., Maejima, Y., Kasama, T., Tamura, N., Nakagama, S., Ito, Y., ... & Sasano, T. (2021). Linagliptin, A Xanthine-Based Dipeptidyl Peptidase-4 Inhibitor, Ameliorates Experimental Autoimmune Myocarditis. JACC: Basic to Translational Science.

      162.Hendrix, R. D., Ou, Y., Davis, J. E., Odle, A. K., Groves, T. R., Allen, A. R., ... & Barger, S. W. (2020). Alzheimer amyloid β-peptide disrupts membrane localization of glucose transporter 1 in astrocytes: Implications for glucose levels in brain and blood. Neurobiology of Aging.

      163.Li, C., Wang, X., Yan, J., Cheng, F., Ma, X., Chen, C., ... & Wang, Q. (2020). Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway. Oxidative Medicine and Cellular Longevity, 2020.

      164.Su, R., Zhang, Y., Zhou, P., Gong, Z., & Lu, F. (2020). ABIN-1 in the brain alleviates opioid tolerance by interacting with β-arrestin2 and MOR. Authorea Preprints.

      165.Wang, Q., Ishizawa, K., Li, J., Fujii, W., Nemoto, Y., Yamazaki, O., ... & Segawa, H. (2020). Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model. Communications Biology, 3(1), 1-12.

      166.Wu, C., Shi, B., Yang, D., Zhang, K., Li, J., Wang, J., ... & Nan, Y. (2020). Porcine Reproductive and Respiratory Syndrome Virus Promotes SLA-DR-Mediated Antigen Presentation of Nonstructural Proteins To Evoke a Nonneutralizing Antibody Response In Vivo. Journal of Virology, 94(21).

      167.Fukuyama, K., & Okada, M. (2020). Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. International Journal of Molecular Sciences, 21(21), 8142.

      168.Imai, M., Kawakami, F., Kubo, M., Kanzaki, M., Maruyama, H., Kawashima, R., ... & Ichikawa, T. (2020). LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance via Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes. Biological and Pharmaceutical Bulletin, 43(11), 1660-1668.

      169.Chen, L., Li, X., Wang, H., Hou, P., & He, H. (2020). Annexin A2 gene interacting with viral matrix protein to promote bovine ephemeral fever virus release. Journal of Veterinary Science, 21(2).

      170.Thapa, N., Chen, M., Horn, H. T., Choi, S., Wen, T., & Anderson, R. A. (2020). Phosphatidylinositol 3-kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4. Nature Cell Biology, 22(11), 1357-1370.

      171.Song, G., Li, L., & Yang, Y. (2020). MicroRNA‑329‑3p alleviates high glucose‑induced endothelial cell injury via inhibition of the TLR4/TRAF6/NF‑κB signaling pathway. Experimental and Therapeutic Medicine, 21(1), 1-1.

      172.Wang, Y., Zhang, X., Wang, T., Liu, W., Wang, L., Hao, L., ... & Xiao, R. (2020). 27-Hydroxycholesterol promotes the transfer of astrocyte-derived cholesterol to neurons in co-cultured SH-SY5Y cells and C6 cells. Frontiers in Cell and Developmental Biology, 8.

      173.Zhao, Z. A., Jiang, Y., Li, L., Chen, Y., Li, Y., Lan, Q., ... & Zhou, P. (2020). Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1. ACS Omega.

      174.Zhang, Y., Yan, L. S., Ding, Y., Cheng, B. C. Y., Luo, G., Kong, J., ... & Zhang, S. F. (2020). Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes. Frontiers in pharmacology, 10, 1666.

      175.Yano, K., Todokoro, I., Kamioka, H., Tomono, T., & Ogihara, T. (2020). Functional alterations of multidrug resistance-associated proteins 2 and 5, and breast cancer resistance protein upon Snail-induced epithelial–mesenchymal transition in HCC827 cells. Biological and Pharmaceutical Bulletin, 44(1), 103-111.

      176.Zhang, H. T., Zeng, Q., Wu, B., Lu, J., Tong, K. L., Lin, J., ... & Gao, X. TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy. Cell Death & Disease, 12(1), 1-14.

      177.Eustaquio Do Imperio, G., Lye, P., Bloise, E., & Matthews, S. G. (2021). Function of Multidrug Resistance Transporters is Disrupted by Infection Mimics in Human Brain Endothelial Cells. Tissue Barriers, 1860616.

      178.Luo, X., Gong, H. B., Gao, H. Y., Wu, Y. P., Sun, W. Y., Li, Z. Q., ... & He, R. R. Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2. Cell Death & Differentiation, 1-19.

      179.Zhang, X. L., Lai, R. C., Chen, Z. H., Zhong, X. X., Cao, X. Y., Zhang, X., ... & Xie, M. X. (2021). Foxo1 selectively regulates static mechanical pain by interacting with Nav1. 7. Pain, 162(2), 490-502.

      180.Bai, H., Zhou, R., Barravecchia, M., Norman, R., Friedman, A., Yu, D., ... & Dean, D. A. (2021). The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα. JCI insight, 6(4).

      181.Okada, M., Matsumoto, R., Yamamoto, Y., & Fukuyama, K. (2021). Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. International Journal of Molecular Sciences, 22(3), 1351.

      182.Mukhopadhyay, S., Biancur, D. E., Parker, S. J., Yamamoto, K., Banh, R. S., Paulo, J. A., ... & Kimmelman, A. C. (2021). Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11. Proceedings of the National Academy of Sciences, 118(6).

      183.Zhang, X., Xu, X., Zhang, Z., Xue, C., Kong, Z., Wu, S., ... & Qin, X. (2021). Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma. International Journal of Biological Sciences, 17(3), 768-780.

      184.Elzi DJ, Bauta WE, Sanchez JR, et al. Identification of a novel mechanism for meso-tetra (4-carboxyphenyl) porphyrin (TCPP) uptake in cancer cells. The FASEB Journal. 2021;35:e21427.

      185.Xie, M. X., Cao, X. Y., Zeng, W. A., Lai, R. C., Guo, L., Wang, J. C., ... & Zhang, X. L. (2021). ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking. Nature Communications, 12(1), 1-18.

      186.Okada, M., Fukuyama, K., Shiroyama, T., & Ueda, Y. (2021). Brivaracetam prevents astroglial l-glutamate release associated with hemichannel through modulation of synaptic vesicle protein. Biomedicine & Pharmacotherapy, 138, 111462.

      187.Taniguchi, T., Omura, K., Motoki, K., Sakai, M., Chikamatsu, N., Ashizawa, N., ... & Iwanaga, T. (2021). Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2. Scientific Reports, 11(1), 1-10.

      188.Bai, L., Wang, Y., Huo, J., Li, S., Wen, Y., Liu, Q., ... & Li, R. (2021). Simvastatin accelerated motoneurons death in SOD1 G93A mice through inhibiting Rab7-mediated maturation of late autophagic vacuoles. Cell Death & Disease, 12(4), 1-17.

      189.Fukuyama, K., Nakano, T., Shiroyama, T., & Okada, M. (2021). Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions. International Journal of Molecular Sciences, 22(8), 4122.

      190.Yano, K., Kimura, M., Watanabe, Y., & Ogihara, T. (2021). Rapid Increase of Gastrointestinal P-Glycoprotein Functional Activity in Response to Etoposide Stimulation. Biological and Pharmaceutical Bulletin, 44(5), 701-706.

      191.Xiu, M., Huan, X., Ou, Y., Ying, S., & Wang, J. (2021). The basic route of nuclear‐targeted transport of IGF‐1/IGF‐1R and potential biological functions in intestinal epithelial cells. Cell Proliferation, e13030.

      192.Xu, J., Wu, S., Wang, J., Wang, J., Yan, Y., Zhu, M., ... & Liu, T. (2021). Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons. Journal of Neuroinflammation, 18(1), 1-17.

      193.Malek, M., Wawrzyniak, A. M., Koch, P., Lüchtenborg, C., Hessenberger, M., Sachsenheimer, T., ... & Haucke, V. (2021). Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites. Nature Communications, 12(1), 1-16.

      194.Dong, X., Li, Y., Li, W., Kang, W., Tang, R., Wu, W., ... & Zhou, L. (2021). The function of Cav-1 in MDA-MB-231 breast cancer cell migration and invasion induced by ectopic ATP5B. Medical Oncology, 38(6), 1-11.

      195.D Shen, C Zhou, M Cao, W Cai, H Yin. (2021). Differential Membrane Protein Profile in Bovine X- and Y‑Sperm.Journal of Proteome Research .

      196.Xiao-Long Zhanga, Jin-Jun Zhangb, Zi-Hang Chenc, Kai-Bin Yangc, Xi Zhangc, Yi-Bin Xiaoc, Yi Leid,
      Xian-Ying Caod,e, Man-Xiu Xie.(2021).Difference of pain vulnerability in adult and juvenile rodents: the role of SIRT1-mediated ClC-3 trafficking in sensory neurons.PAIN: June 2021 - Volume 162 - Issue 6 - p 1882-1896 doi: 10.1097/j.pain.0000000000002176

      197.Zhou Y, Nie AQ, Chen S, Wang MM, Yin R, Tang BH, Wu YE, Yang F, Du B, Shi HY, Yang XM, Hao GX, Guo XL, Han QJ, Zheng Y, Zhao W. Downregulation of Renal MRPs Transporters in Acute Lymphoblastic Leukemia Mediated by the IL-6/STAT3/PXR Signaling Pathway. J Inflamm Res. 2021;14:2239-2252.https://doi.org/10.2147/JIR.S310687

      198.Fukuyama, K., & Okada, M. (2021). Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin43. International Journal of Molecular Sciences, 22(11), 5623.

      199.Kongshuo Ma, Guohua Qi, Bo Wang, Tengfei Yu,Ying Zhang, Haijuan Li, Shimeles Addisu Kitte and Yongdong Jin, Ultrasound-activated Au/ZnO-based Trojan nanogenerators for combined targeted electrostimulation and enhanced catalytic therapy of tumor, Nano Energy, (2021).doi:https://doi.org/10.1016/j.nanoen.2021.106208

      200.Fu et al., OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin, Molecular Cell (2021), https://doi.org/10.1016/j.molcel.2021.05.031

      201.Xing, Y. J., Liu, B. H., Wan, S. J., Cheng, Y., Zhou, S. M., Sun, Y., ... & Kong, X. (2021). A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitro. Frontiers in Pharmacology, 12, 1756.

      202.Notas, G., Panagiotopoulos, A., Vamvoukaki, R., Kalyvianaki, K., Kiagiadaki, F., Deli, A., ... & Castanas, E. (2021). ERα36–GPER1 Collaboration Inhibits TLR4/NFκB-Induced Pro-Inflammatory Activity in Breast Cancer Cells. International Journal of Molecular Sciences, 22(14), 7603.

      203.Heidasch, R., Avci, D., Lüchtenborg, C., Kale, D., Beard, H., Mentrup, T., ... & Lemberg, M. K. (2021). Intramembrane protease SPP defines a cholesterol-regulated switch of the mevalonate pathway. bioRxiv.

      204.Li, Y., Sun, X. L., Ma, C. L., Li, C., Zhan, Y., Li, W. T., ... & Wang, Y. H. (2021). STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in Preeclampsia. Frontiers in Cell and Developmental Biology, 9.

      205.Ochiai-Homma, F., Kuribayashi-Okuma, E., Tsurutani, Y., Ishizawa, K., Fujii, W., Odajima, K., ... & Shibata, S. (2021). Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism. Hypertension Research, 1-11.

      206.Li, H., Cao, W., Zhang, X. B., Zhang, X. X., Gu, C., Gu, L. M., ... & Lu, M. (2021). Atractylenolide‑1 alleviates gastroparesis in diabetic rats by activating the stem cell factor/c‑kit signaling pathway. Molecular Medicine Reports, 24(4), 1-10.

      207.Xingyi Xu; Rongyuan Zhang; Xianfeng Yang; Yao Lu; Zhongmin Yang; et al(2021)A Honeycomb‐Like Bismuth/Manganese Oxide Nanoparticle with Mutual Reinforcement of Internal and External Response for Triple‐Negative Breast Cancer Targeted Therapy.Advanced Healthcare Materials.

      208.Li, Y., Tang, W., Kang, L., Kong, S., Dong, Z., Zhao, D., ... & Yu, S. (2021). Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms. The Journal of Headache and Pain, 22(1), 1-12.

      209.Hayashi, S., & Kakikawa, M. (2021). Exposure to 60 Hz magnetic field can affect membrane proteins and membrane potential in human cancer cells. Electromagnetic Biology and Medicine, 1-8.

      210.Makoto Osada, Keiko Maruyama, Koichi Kokame, Ryunosuke Denda, Kohei Yamazaki, Hisako Kunieda, Maki Hirao, Seiji Madoiwa, Nobuo Okumura, Mitsuru Murata, Yasuo Ikeda, Kentaro Watanabe, Yuiko Tsukada, Takahide Kikuchi; A novel homozygous variant of the thrombomodulin gene causes a hereditary bleeding disorder. Blood Adv 2021; bloodadvances.2020003814. doi: https://doi.org/10.1182/bloodadvances.2020003814

      211.Yixin Zhang, Peilan Zhou, Fengfeng Lu, Ruibin Su and Zehui Gong.A20-Binding Inhibitor of Nuclear Factor-κB Targets β-Arrestin2 to Attenuate Opioid Tolerance.

      214.Li, Q., Lu, B., Yang, J., Li, C., Li, Y., Chen, H., ... & Xia, W. (2021). Molecular Characterization of an Aquaporin− 2 Mutation Causing Nephrogenic Diabetes Insipidus. Frontiers in Endocrinology, 12

      215.Shiroyama, T., Fukuyama, K., & Okada, M. (2021). Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. International Journal of Molecular Sciences, 22(18), 10013.

      216.Yapeng Hou, Jun Li, Yan Ding, Yong Cui, Hongguang Nie,Luteolin attenuates lipopolysaccharide-induced acute lung injury/acute respiratory distress syndrome by activating alveolar epithelial sodium channels via cGMP/PI3K pathway,Journal of Ethnopharmacology

      217.Zhao, M. M., Lu, J., Li, S., Wang, H., Cao, X., Li, Q., ... & Yang, J. K. (2021). Berberine is an insulin secretagogue targeting the KCNH6 potassium channel. Nature Communications, 12(1), 1-14.

      218.Liu, D., Yang, L., Liu, P., Ji, X., Qi, X., Wang, Z., ... & Zou, L. (2021). Sigma–1 receptor activation alleviates blood–brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF–GFRα1–RET pathway. Experimental Neurology, 113867.

      219.Gad, S. A., Sugiyama, M., Tsuge, M., Wakae, K., Fukano, K., Oshima, M., ... & Aly, H. H. (2022). The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro. PLoS pathogens, 18(3), e1009983.

      220.Chen, D., Zheng, Q., Sun, L., Ji, M., Li, Y., Deng, H., & Zhang, H. (2021). ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress. Developmental Cell.

      221.Niu, M., Xu, J., Liu, Y., Li, Y., He, T., Ding, L., ... & Xiao, Z. X. J. (2021). FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth. Nature Communications, 12(1), 1-15.

      222.Müller, G. A., Tschöp, M. H., & Müller, T. D. (2021). Chip-Based Sensing of the Intercellular Transfer of Cell Surface Proteins: Regulation by the Metabolic State. Biomedicines, 9(10), 1452.

      223.Kang, K., Zhang, M., Yue, L., Chen, W., Dai, Y., Lin, K., ... & Zhang, W. (2021). Oxalic acid binds to gustatory receptor Gr23a and inhibits feeding in the brown planthopper. bioRxiv.

      224.Haokun Guo, Yan Liu, Juan Gu, Jing Luo, Yuanlin Ma, Fei Xiao,GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1,Biochemical and Biophysical Research Communications,Volume 582,2021

      225.Rodriguez, R., Lee, A. Y., Godoy-Lugo, J. A., Martinez, B., Ohsaki, H., Nakano, D., ... & Ortiz, R. M. (2021). Chronic AT1 blockade improves hyperglycemia by decreasing adipocyte inflammation and decreasing hepatic PCK1 and G6PC1 expression in obese rats. American Journal of Physiology-Endocrinology and Metabolism.

      226.Wang, T. Z., Zuo, G. W., Yao, L., Yuan, C. L., Li, H. F., Lai, Y., ... & Wang, J. W. (2021). Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Akt‑glucose transporter 4 signaling pathway and inhibiting inflammation. Experimental and Therapeutic Medicine, 22(6), 1-9.

      227.Bianchi-Smiraglia, A., Wolff, D. W., Marston, D. J., Deng, Z., Han, Z., Moparthy, S., ... & Nikiforov, M. A. (2021). Regulation of local GTP availability controls RAC1 activity and cell invasion. Nature communications, 12(1), 1-15.

      228.Muthusamy, S., Jan, H. M., Hsieh, M. Y., Mondal, S., Liu, W. C., Ko, Y. A., ... & Lin, C. H. (2021). Enhanced enzymatic production of cholesteryl 6ʹ-acylglucoside impairs lysosomal degradation for the intracellular survival of Helicobacter pylori. Journal of Biomedical Science, 28(1), 1-20.

      229.Hayata-Takano, A., Shintani, Y., Moriguchi, K., Encho, N., Kitagawa, K., Nakazawa, T., & Hashimoto, H. (2021). PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization. Frontiers in Endocrinology, 1331.

      230.Fukuyama, K., & Okada, M. (2021). Effects of an Atypical Antipsychotic, Zotepine, on Astroglial L-Glutamate Release through Hemichannels: Exploring the Mechanism of Mood-Stabilising Antipsychotic Actions and Antipsychotic-Induced Convulsion. Pharmaceuticals, 14(11), 1116.

      231.Yang, B., Jiang, Q., He, S., Li, T., Ou, X., Chen, T., ... & Tan, X. (2021). Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-1. Journal of Molecular and Cellular Cardiology.

      232.Wang, J., Liu, B., He, Y., Li, Z., Zhao, Q., Nan, Y., & Wu, C. (2021). Porcine epidemic diarrhea Virus envelope protein blocks SLA-DR expression in barrow-derived dendritic cells by inhibiting promoters activation. Frontiers in Immunology, 4748.

      233.Zhang, L., Yu, X., Wu, Y., Fu, H., Xu, P., Zheng, Y., ... & Baker, P. N. (2021). Gestational Diabetes Mellitus-Associated Hyperglycemia Impairs Glucose Transporter 3 Trafficking in Trophoblasts Through the Downregulation of AMP-Activated Protein Kinase. Frontiers in cell and developmental biology, 9.

      234.Hosoya, T., Uchida, S., Shibata, S., Tomioka, N., Matsumoto, K., & Hosoyamada, M. (2021). Xanthine Oxidoreductase Inhibitors Suppress the Onset of Exercise-induced AKI in High HPRT Activity Urat1-Uox Double Knockout Mice. Journal of the American Society of Nephrology.

      235.Zhang, N., Zhu, H., Li, Z., & Dong, E. (2021). A novel β2-AR agonist, Higenamine, induces β-arrestin-biased signaling. Science China Life Sciences, 1-12.

      236.Song, Y., Huang, H., Hu, Y., Zhang, J., Li, F., Yin, X., ... & Chen, H. (2021). A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. PLoS pathogens, 17(12), e1010141.

      237.Ying, L., Wang, L., Guo, K., Hou, Y., Li, N., Wang, S., ... & Huang, Z. (2021). Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects. Nature Communications, 12(1), 1-14.

      238.Zhang, M., Yang, H., Yang, E., Li, J., & Dong, L. (2022). Berberine Decreases Intestinal GLUT2 Translocation and Reduces Intestinal Glucose Absorption in Mice. International Journal of Molecular Sciences, 23(1), 327.

      239.Chen, Y., Wu, X., Zhang, J., Pan, G., Wang, X., Guo, X., ... & Jiang, F. Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance. EMBO reports, e53373.

      240.Chen, H., McKeen, T., Chao, X., Chen, A., Deng, F., Jaeschke, H., ... & Ni, H. M. (2022). The role of MLKL in Hepatic Ischemia-Reperfusion Injury of Alcoholic Steatotic Livers. International Journal of Biological Sciences, 18(3), 1096-1106.

      241.Wang, J., Luo, J., Wen, Z., Wang, X., Shuai, L., Zhong, G., ... & Bu, Z. (2022). Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor. mBio, 13(1), e02443-21.

      242.Xu, Y., Cheng, S., Zeng, H.et al. ARF GTPases activateSalmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy.Nat Struct Mol Biol.29,67–77 (2022).https://doi.org/10.1038/s41594-021-00710-6

      243.Zhang, H., Liang, A., & Pan, X. (2022). Preparation and Functional Identification of a Novel Conotoxin QcMNCL-XIII0. 1 from Conus quercinus. Toxins, 14(2), 99.

      244.Huang, F., Tang, X., Ye, B., Wu, S., & Ding, K. (2022). PSL-LCCL: a resource for subcellular protein localization in liver cancer cell line SK_HEP1. Database, 2022.

      245.Son, Y., Choi, C., Saha, A., Park, J. H., Im, H., Cho, Y. K., ... & Lee, Y. H. (2022). REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction. Metabolism, 155159.

      246.ennakoon, N., Ryu, J., Ujike, M., Taguchi, F., & Shin, H. J. (2022). Reduction of Cell Fusion by Deletion in the Hypervariable Region of the Spike Protein of Mouse Hepatitis Virus. Viruses, 14(2), 398.

      247.Choi, K. J., Lee, J. H., Park, S. B., Na, Y. J., Jung, W. H., Lee, H., & Kim, K. Y. (2022). Development of in vitro three-dimensional drug screening system for obesity-related metabolic syndrome. Journal of Pharmacological Sciences.

      248.Wang, X., Luo, J., Wen, Z., Shuai, L., Wang, C., Zhong, G., ... & Bu, Z. (2022). Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung. PLoS pathogens, 18(2), e1010343

      249.Shen, H., Xu, X., Fu, Z., Xu, C., & Wang, Y. (2022). The interactions of CAP and LYN with the insulin signaling transducer CBL play an important role in polycystic ovary syndrome. Metabolism, 155164.

      250.Fukuyama, K., Motomura, E., Shiroyama, T., & Okada, M. (2022). Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gain. Biomedicine & Pharmacotherapy, 148, 112750.

      251.Shen, Q., Wu, X., Zhang, Z., Zhang, D., Yang, S., & Xing, D. Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β‐amyloid load in Alzheimer's disease model. Aging Cell, e13573.

      252. Cheng, Y., Kang, X. Z., Cheng, T., Ye, Z. W., Tipoe, G. L., Yu, C. H., ... & Jin, D. Y. (2022). FACI Is a Novel CREB-H–Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity. Cellular and Molecular Gastroenterology and Hepatology.

      253.Zeng, C., Xia, T., Zheng, S., Liang, L., & Chen, Y. (2022). Synergistic Effect of Uroguanylin and D1 Dopamine Receptors on Sodium Excretion in Hypertension. Journal of the American Heart Association, e022827.

      254.Fukuyama, K., & Okada, M. (2022). High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings. Biomedicine & Pharmacotherapy, 149, 112846.

      255.Bhattacharya, I., Yadavalli, T., Wu, D., & Shukla, D. (2022). Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1. Viruses, 14(4), 799.

      256.Li, Y., Wei, J. Y., Liu, H., Wang, K. J., Jin, S. N., Su, Z. K., ... & Chen, Y. H. (2022). An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity. Cell Reports, 39(2), 110656.

      257.James C. S. Ho, Sartaj Ahmad Mir.(2022).Lipid bilayer composition as a determinant of cancer cell sensitivity to tumoricidal protein-lipid complexes.BioFactors.

      258.Attenuation of ROS/Chloride Efflux-Mediated NLRP3 Inflammasome Activation Contributes to Alleviation of Diabetic Cardiomyopathy in Rats after Sleeve Gastrectomy. Oxidative Medicine and Cellular Longevity, 2022.

      259.Fukuyama, K.; Okada, M.(2022)Brivaracetam and Levetiracetam Suppress Astroglial L-Glutamate Release through Hemichannel via Inhibition of Synaptic Vesicle Protein. Int. J. Mol. Sci. 2022, 23, 4473.https://doi.org/10.3390/ijms23094473

      260.Alam, M. B., Ra, J. S., Lim, J. Y., Song, B. R., Javed, A., & Lee, S. H. Lariciresinol displays anti‐diabetic activity through inhibition of α‐glucosidase and activation and enhancement of insulin signaling. Molecular Nutrition & Food Research, 2100751.

      261.Caroline O. Tabler; Sarah J. Wegman; Jiji Chen; Hari Shroff; Najwa Alhusaini; et al(2022).The HIV-1 Viral Protease Is Activated during Assembly and Budding Prior to Particle Release.Journal of Virology.

      262.Wang, H., Dai, Y., Clark, N., Boeglin, L., Woo, C., Wooster, R., ... & Sullivan, J. C. (2022). Targeted quantitation of CFTR protein expression in vivo using immunoprecipitation & parallel reaction monitoring tandem mass spectrometry. Translational Medicine Communications, 7(1), 1-11.

      263. Yoo, A., Joo, Y., Cheon, Y., Lee, S. J., & Lee, S. (2022). Neuronal growth regulator 1 promotes adipocyte lipid trafficking via interaction with CD36. Journal of Lipid Research, 100221.

      264.Li, F., Chen, T., Wang, F., Chen, J., Zhang, Y., Song, D., ... & Zhuang, J. (2022). Enhanced Cancer Starvation Therapy Enabled by an Autophagy Inhibitors-Encapsulated Biomimetic ZIF-8 Nanodrug: Disrupting and Harnessing Dual Pro-Survival Autophagic Responses. ACS Applied Materials & Interfaces.

      265.Cao, X., Shao, Y., Meng, P., Cao, Z., Yan, G., Yao, J., ... & Lu, H. (2022). Nascent Proteome and Glycoproteome Reveal the Inhibition Role of ALG1 in Hepatocellular Carcinoma Cell Migration. Phenomics, 1-12.

      266.Lv Y-Y,Wang H, Fan H-T,Xu T, XinW-J,Guo R-X.SUMOylation of Kir7.1 participates in neuropathic pain through regulating its membrane expression in spinal cord neurons. CNS Neurosci Ther.2022;00:1-9.doi: 10.1111/cns.13871

      267.Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; et al(2022).Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats.Neuroscience Bulletin.

      268.Li, Weili, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Ye Yuan, and Yuying Fan. (2022).Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy. (2022)

      269.Liu, Y., Tian, X., Ke, P. et al. KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B. Neurosci. Bull. (2022). https://doi.org/10.1007/s12264-022-00888-9

      270.Fukuyama, K., Motomura, E., & Okada, M. (2022). Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems. International Journal of Molecular Sciences, 23(12), 6571.

      271.Song, B. R., Alam, M. B., & Lee, S. H. (2022). Terpenoid-Rich Extract of Dillenia indica L. Bark Displays Antidiabetic Action in Insulin-Resistant C2C12 Cells and STZ-Induced Diabetic Mice by Attenuation of Oxidative Stress. Antioxidants, 11(7), 1227.





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